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Query author contributions in Reactome

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Details on Person IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol]

Class:IdComplex:177663
_displayNameIKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol]
_timestamp2017-07-13 16:40:33
authored[InstanceEdit:167907] Luo, F, 2005-11-10 11:23:18
compartment[Compartment:70101] cytosol
created[InstanceEdit:177664] Gillespie, ME, 2006-04-03 21:05:10
hasComponent
literatureReference[LiteratureReference:5607847] IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
[LiteratureReference:8867307] The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component
modified[InstanceEdit:205151] Gillespie, ME, 2007-12-07 19:07:11
[InstanceEdit:8867314] Shamovsky, Veronica, 2016-04-06
[InstanceEdit:9012434] Duenas, Corina, 2017-07-13
nameIKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB
Activated IKK Complex
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:369070] R-HSA-177663.3
summation[Summation:8867304] Co-immunoprecipitation studies and size exclusion chromatogr...
(activeUnit)[CatalystActivity:9820495] protein serine/threonine kinase activity of TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane]
(hasComponent)[Complex:9818787] TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] [Homo sapiens]
[Complex:9818791] TNFα:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:5262890] partial_loss_of_function of TNFalpha associated IKBKG variants [cytosol]
(output)[Reaction:168910] RIP1 facilitates IKK complex phosphorylation [Homo sapiens]
[Reaction:933530] Activation of IKK by MEKK1 [Homo sapiens]
(physicalEntity)[CatalystActivity:450351] protein serine/threonine kinase activity of IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol]
[CatalystActivity:451612] IkappaB kinase activity of IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol]
(updatedInstance)[_UpdateTracker:9866625] Update Tracker - [Complex:177663] IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] - v24:[add_removeHasComponent]
[_UpdateTracker:9894353] Update Tracker - [Complex:177663] IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] - v57:[addLiteratureReference, addSummation]
[_UpdateTracker:9897652] Update Tracker - [Complex:177663] IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] - v62:[addName]
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No pathways have been reviewed or authored by IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol] (177663)
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