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Details on Person phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate

Class:IdReaction:177157
_displayNamephenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate
_doReleaseTRUE
_timestamp2016-11-10 00:55:18
catalystActivity[CatalystActivity:177146] CoA-ligase activity of xenobiotic/medium-chain fatty acid:CoA ligases [mitochondrial matrix]
compartment[Compartment:5460] mitochondrial matrix
created[InstanceEdit:177120] D'Eustachio, P, 2006-03-23 20:05:02
edited[InstanceEdit:177133] D'Eustachio, P, 2006-03-23 15:51:01
input[SimpleEntity:177153] phenylacetate [mitochondrial matrix]
[SimpleEntity:113593] ATP [mitochondrial matrix]
[SimpleEntity:29374] CoA-SH [mitochondrial matrix]
literatureReference[LiteratureReference:159570] Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acids
[LiteratureReference:159552] Isolation, sequencing, and expression of a cDNA for the HXM-A form of xenobiotic/medium-chain fatty acid:CoA ligase from human liver mitochondria
[LiteratureReference:177141] Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product
modified[InstanceEdit:177163] D'Eustachio, P, 2006-03-23 20:35:35
[InstanceEdit:177295] D'Eustachio, P, 2006-03-27 18:47:31
[InstanceEdit:211333] D'Eustachio, P, 2008-01-31 19:12:03
[InstanceEdit:353652] Jassal, Bijay, 2008-06-13
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namephenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate
Synthesis of phenylacetyl CoA from phenylacetate and Coenzyme A
output[SimpleEntity:177137] phenylacetyl-CoA [mitochondrial matrix]
[SimpleEntity:159448] AMP [mitochondrial matrix]
[SimpleEntity:159450] PPi [mitochondrial matrix]
releaseDate2006-04-24
reviewed[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360125] R-HSA-177157.3
summation[Summation:177140] Phenylacetate and ATP react with coenzyme A to form phenylac...
(hasEvent)[Pathway:177162] Conjugation of phenylacetate with glutamine [Homo sapiens]
(precedingEvent)[Reaction:177160] phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A [Homo sapiens]
[Reaction:9971063] GLYAT-like proteins transfer glycine to phenylacetyl-CoA [Homo sapiens]
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No pathways have been reviewed or authored by phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (177157)