Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person I-SMADs are adaptor proteins that bind with phosphatases and...
| Class:Id | Summation:177098 |
|---|---|
| _displayName | I-SMADs are adaptor proteins that bind with phosphatases and... |
| _timestamp | 2006-04-18 14:30:26 |
| created | [InstanceEdit:177100] Jassal, B, 2006-03-22 11:41:32 |
| modified | [InstanceEdit:178236] Jassal, B, 2006-04-18 14:30:18 |
| text | I-SMADs are adaptor proteins that bind with phosphatases and/or ubiquitin ligases (e.g. Smurfs) as well as type I receptors. These enzymes de-phosphorylate or ubiquitinate the type I receptor, thus leading to receptor inactivation and ultimate degradation in lysosomes upon endocytosis (the latter events are not shown in the Reactome pathway). |
| (summation) | [Pathway:177106] I-SMAD recruits type I receptor phosphatase and ubiquitin ligases to mediate receptor downregulation [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by I-SMADs are adaptor proteins that bind with phosphatases and... (177098)
