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Details on Person UniProt:Q7ZT46 gins2
| Class:Id | ReferenceGeneProduct:176965 |
|---|---|
| _chainChangeLog | chain:1-185 added on Sat February 7 2015 |
| _displayName | UniProt:Q7ZT46 gins2 |
| _timestamp | 2024-08-09 18:55:32 |
| chain | chain:1-185 |
| checksum | F6DAC1CC608F5FD0 |
| comment | FUNCTION Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.SUBUNIT Component of the GINS complex which is a heterotetramer of gins1/psf1, gins2/psf2, gins3/psf3 and gins4/sld5 (PubMed:12730133). Component of the CMG helicase complex, composed of the mcm2-7 complex, the GINS complex and cdc45 (Probable) (PubMed:30979826).SUBCELLULAR LOCATION Associates with chromatin.SIMILARITY Belongs to the GINS2/PSF2 family. |
| created | [InstanceEdit:176962] Gopinathrao, G, 2006-03-17 19:09:52 |
| description | recommendedName: DNA replication complex GINS protein PSF2 alternativeName: GINS complex subunit 2 |
| geneName | gins2 psf2 |
| identifier | Q7ZT46 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Chromosome DNA replication Nucleus Reference proteome |
| modified | [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9715482] Weiser, JD [InstanceEdit:9796772] Weiser, Joel [InstanceEdit:9819394] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9909836] Weiser, Joel, 2024-05-14 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 |
| name | gins2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PSF2_XENLA Q6GPR6 |
| sequenceLength | 185 |
| species | [Species:51320] Xenopus laevis |
| (referenceEntity) | [EntityWithAccessionedSequence:176946] xPSF1p [nucleoplasm] [Xenopus laevis] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q7ZT46 gins2 (176965)
