Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person One model ( the direct inhibition model) describing the inhi...

Class:IdSummation:176817
_displayNameOne model ( the direct inhibition model) describing the inhi...
_timestamp2006-04-09 23:11:14
created[InstanceEdit:176815] Matthews, L, 2006-03-13 00:04:30
modified[InstanceEdit:176931] Matthews, L, 2006-03-16 21:34:06
[InstanceEdit:177821] Matthews, L, 2006-04-09 23:10:38
textOne model ( the direct inhibition model) describing the inhibition of the APC/C during the mitotic spindle checkpoint suggests that the association of the hBUBR1:hBUB3:MAD2*:CDC20 mitotic checkpoint complex (MCC) with APC/C results in the inactivation of APC/C. The affinity between MCC and APC/C is not high, thus inhibition is readily reversible when the mitotic spindle checkpoint has been satisfied.
(summation)[Reaction:174238] Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by One model ( the direct inhibition model) describing the inhi... (176817)