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Details on Person RAD17:RFC [nucleoplasm]
Class:Id Complex:176353
_displayName RAD17:RFC [nucleoplasm]
_timestamp 2015-03-23 19:50:50
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:176246] D'Eustachio, P, 2006-03-03 16:44:08
hasComponent
modified [InstanceEdit:3008669] Jassal, B, 2013-02-01 [InstanceEdit:5684885] Orlic-Milacic, Marija, 2015-03-23
name RAD17:RFC Rad17-RFC complex
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:364239] R-HSA-176353.1
summation [Summation:176173] The Rad17-RFC complex is a heteropentamer structurally simil...
(hasComponent) [Complex:176204] Rad17-RFC complex bound to DNA [nucleoplasm] [Homo sapiens] [Complex:5684883] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] [Homo sapiens] [Complex:5685039] ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens] [Complex:5685162] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens] [Complex:5686616] ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens] [Complex:9980022] ATR:ATRIP:p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens] [Complex:9980181] ATR:ATRIP:p-RPA:SSB-HHV8 dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens]
(input) [Reaction:176101] Recruitment of Rad17-RFC complex to DNA [Homo sapiens] [Reaction:5685011] ATR activation at DNA DSBs [Homo sapiens]
(output) [BlackBoxEvent:5686663] Completion of SSA [Homo sapiens] [Reaction:5693561] RAD51 binds BRCA2 at resected DNA DSBs [Homo sapiens]
(updatedInstance) [_UpdateTracker:9877285] Update Tracker - [Complex:176353] RAD17:RFC [nucleoplasm] - v44:[add_removeHasComponent] [_UpdateTracker:9892575] Update Tracker - [Complex:176353] RAD17:RFC [nucleoplasm] - v53:[addName]
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Protein identifiers
No pathways have been reviewed or authored by RAD17:RFC [nucleoplasm] (176353)