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Details on Person RAD9:HUS1:RAD1 [nucleoplasm]
Class:Id Complex:176312
_displayName RAD9:HUS1:RAD1 [nucleoplasm]
_timestamp 2015-03-23 19:50:50
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:176246] D'Eustachio, P, 2006-03-03 16:44:08
hasComponent
literatureReference [LiteratureReference:176375] Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy
modified [InstanceEdit:5684885] Orlic-Milacic, Marija, 2015-03-23
name RAD9:HUS1:RAD1 Rad9-Hus1-Rad1 complex 9-1-1 complex
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:370102] R-HSA-176312.1
summation [Summation:176248] The Rad9-Hus1-Rad1 (9-1-1) complex is a ring-shaped heterotr...
(hasComponent) [Complex:176256] Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] [Homo sapiens] [Complex:5684883] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] [Homo sapiens] [Complex:5685039] ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens] [Complex:5685162] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens] [Complex:5686616] ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens] [Complex:9980022] ATR:ATRIP:p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens] [Complex:9980181] ATR:ATRIP:p-RPA:SSB-HHV8 dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens]
(input) [Reaction:176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA [Homo sapiens] [Reaction:5685011] ATR activation at DNA DSBs [Homo sapiens]
(output) [BlackBoxEvent:5686663] Completion of SSA [Homo sapiens] [Reaction:5693561] RAD51 binds BRCA2 at resected DNA DSBs [Homo sapiens]
(updatedInstance) [_UpdateTracker:9867095] Update Tracker - [Complex:176312] RAD9:HUS1:RAD1 [nucleoplasm] - v25:[updateContainedComponent] [_UpdateTracker:9892536] Update Tracker - [Complex:176312] RAD9:HUS1:RAD1 [nucleoplasm] - v53:[addName]
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Protein identifiers
No pathways have been reviewed or authored by RAD9:HUS1:RAD1 [nucleoplasm] (176312)