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Details on Person Activation of claspin

Class:IdReaction:176298
_displayNameActivation of claspin
_doReleaseTRUE
_timestamp2016-11-10 00:55:31
authored[InstanceEdit:176227] Borowiec, JA, 2006-02-25 17:40:15
catalystActivity[CatalystActivity:176203] protein serine/threonine kinase activity of ATR:ATRIP [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:176246] D'Eustachio, P, 2006-03-03 16:44:08
edited[InstanceEdit:176160] D'Eustachio, P, 2006-02-25 17:41:28
goBiologicalProcess[GO_BiologicalProcess:7962] DNA replication
input[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
[Complex:176229] Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:176239] DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system
modified[InstanceEdit:177296] D'Eustachio, P, 2006-03-27 18:48:54
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivation of claspin
output[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[Complex:176182] Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2006-04-24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359656] R-HSA-176298.3
summation[Summation:176367] Claspin is a replication fork-associated protein important f...
(hasEvent)[Pathway:176187] Activation of ATR in response to replication stress [Homo sapiens]
(precedingEvent)[Reaction:176116] Recruitment and activation of Chk1 [Homo sapiens]
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No pathways have been reviewed or authored by Activation of claspin (176298)