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Details on Person NNMT transfers CH3 from AdoMet to PY

Class:Id	Reaction:175987
_displayName	NNMT transfers CH3 from AdoMet to PY
_doRelease	TRUE
_timestamp	2017-04-07 15:53:51
catalystActivity	[CatalystActivity:175975] pyridine N-methyltransferase activity of NNMT [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:175984] Jassal, B, 2006-02-27 14:53:40
input	[SimpleEntity:175973] PY [cytosol] [SimpleEntity:71284] AdoMet [cytosol]
literatureReference	[LiteratureReference:8984501] A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase
modified	[InstanceEdit:176090] Jassal, B, 2006-03-03 14:06:57 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:353652] Jassal, Bijay, 2008-06-13 [InstanceEdit:5603083] Jassal, Bijay, 2014-06-27 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8984569] Duenas, Corina, 2017-04-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NNMT transfers CH3 from AdoMet to PY Pyridine can be N-methylated
output	[SimpleEntity:71285] AdoHcy [cytosol] [SimpleEntity:175979] MP+ [cytosol]
precedingEvent	[Reaction:174391] MAT1A multimers transfer Ado from ATP to L-Met [Homo sapiens] [Reaction:1614654] BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY [Homo sapiens] [Reaction:5696838] BHMT2 tetramer transfers CH3 group from SMM to LHCYS [Homo sapiens] [Reaction:174374] MTR transfers CH3 from MeCbl to HCYS [Homo sapiens] [Reaction:1237102] Transamination of MOB to methionine [Homo sapiens] [Reaction:5603114] MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met [Homo sapiens]
releaseDate	2005-04-11
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358838] R-HSA-175987.4
summation	[Summation:176089] Pyridine is a typical substrate for Nicotinamide N-methyltra...
(hasEvent)	[Pathway:156581] Methylation [Homo sapiens]
(precedingEvent)	[Reaction:174401] AHCY:NAD+ tetramer hydrolyses AdoHcy [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781188] Update Tracker - [Reaction:175987] NNMT transfers CH3 from AdoMet to PY - v61:[addLiteratureReference, modifyText]
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