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Query author contributions in Reactome

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Details on Person Wrana, JL

Class:IdPerson:175967
_displayNameWrana, JL
_timestamp2012-01-15 22:29:45
created[InstanceEdit:175950] Jassal, B, 2006-02-27 11:21:52
firstnameJeffrey L
initialJL
modified[InstanceEdit:2031339] Orlic-Milacic, M, 2012-01-05
[InstanceEdit:2060325] D'Eustachio, P, 2012-01-15
surnameWrana
(author)[LiteratureReference:175951] SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor
[LiteratureReference:175963] Mechanism of activation of the TGF-beta receptor
[LiteratureReference:177254] TGF beta signals through a heteromeric protein kinase receptor complex
[LiteratureReference:177257] MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
[LiteratureReference:178152] The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
[LiteratureReference:178212] Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
[LiteratureReference:178228] Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation
[LiteratureReference:202620] MADR1, a MAD-related protein that functions in BMP2 signaling pathways
[LiteratureReference:202636] A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation
[LiteratureReference:208059] GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex
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No pathways have been reviewed or authored by Wrana, JL (175967)
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