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Details on Person Mechanism of activation of the TGF-beta receptor

Class:IdLiteratureReference:175963
_displayNameMechanism of activation of the TGF-beta receptor
_timestamp2006-02-27 11:22:30
author[Person:175967] Wrana, JL
[Person:175972] Attisano, L
[Person:175961] Wieser, R
[Person:175955] Ventura, F
[Person:173487] Massague, J
created[InstanceEdit:175950] Jassal, B, 2006-02-27 11:21:52
journalNature
pages341-7
pubMedIdentifier8047140
titleMechanism of activation of the TGF-beta receptor
volume370
year1994
(literatureReference)[Reaction:170843] TGFBR2 phosphorylates TGFBR1 [Homo sapiens]
[Reaction:208968] TGFBR2 phosphorylates TGFBR1 in the TGFBR2 dimer:TGFB1 dimer:TGFBR1 dimer complex [Homo sapiens]
[Pathway:2173789] TGF-beta receptor signaling activates SMADs [Homo sapiens]
[Pathway:9846196] GOCAM TGF-beta receptor signaling activates SMADs [Homo sapiens]
[Reaction:9846197] GOCAM TGFBR2 phosphorylates TGFBR1 [Homo sapiens]
[Summation:176016] Formation of the hetero-tetrameric TGF-beta-1 receptor compl...
[Summation:2190597] Binding of transforming growth factor beta 1 (TGF beta 1, i....
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