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Details on Person Target DNA binding

Class:Id	Reaction:175108
_displayName	Target DNA binding
_doRelease	TRUE
_timestamp	2016-11-10 00:54:58
authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:175576] Gopinathrao, G, 2006-02-23 23:50:37
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
figure	[Figure:188489] /figures/integ_cleavage.jpg
input	[Complex:175416] IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm] [Homo sapiens] [GenomeEncodedEntity:175158] Host genomic DNA [nucleoplasm] [Homo sapiens]
literatureReference	[Book:175927] 9780879695712 Integration Retroviruses Coffin, JM [LiteratureReference:177403] Retroviral DNA integration--mechanism and consequences [LiteratureReference:177396] Genome-wide analysis of retroviral DNA integration
modified	[InstanceEdit:175638] Gopinathrao, G, 2006-02-25 14:03:09 [InstanceEdit:175936] Gopinathrao, G, 2006-02-25 14:09:53 [InstanceEdit:176739] Gopinathrao, G, 2006-03-10 15:27:37 [InstanceEdit:177399] Gopinathrao, G, 2006-03-29 16:14:14 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:177549] Gopinathrao, G, 2006-04-02 12:03:28 [InstanceEdit:180083] Gopinathrao, G, 2006-05-16 19:02:00 [InstanceEdit:180402] Gopinathrao, G, 2006-05-18 20:43:08 [InstanceEdit:182890] Gopinathrao, G, 2006-07-20 19:02:21 [InstanceEdit:188431] Gopinathrao, G, 2006-10-12 14:53:00 [InstanceEdit:188491] Gopinathrao, G, 2006-10-16 14:30:47 [InstanceEdit:188941] Gopinathrao, G, 2006-10-30 22:24:14 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Target DNA binding
output	[Complex:175224] IN:viral DNA bound to host genomic DNA with staggered ends [nucleoplasm] [Homo sapiens] [Complex:177527] viral PIC proteins [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:162590] Import of PIC to the Host Nucleus [Homo sapiens] [Reaction:164522] Terminal (3' end) cleavage of viral DNA [Homo sapiens] [Reaction:180622] Vpr binds nucleoporins [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-04-11
reviewed	[InstanceEdit:188934] Bushman, FD, 2006-10-30 22:19:13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361982] R-HSA-175108.3
summation	[Summation:180098] How the PIC finds favored sites on target DNA has not been f...
(hasEvent)	[Pathway:175567] Integration of viral DNA into host genomic DNA [Homo sapiens]
(precedingEvent)	[Reaction:164523] Transesterification to connect viral DNA 3' ends to host DNA 5' ends [Homo sapiens]
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No pathways have been reviewed or authored by Target DNA binding (175108)