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Details on Person NAT2 acetylation
Class:Id Reaction:174967
_displayName NAT2 acetylation
_doRelease TRUE
_timestamp 2017-04-10 11:16:19
catalystActivity [CatalystActivity:158690] arylamine N-acetyltransferase activity of AcC-NAT2 [cytosol]
compartment [Compartment:70101] cytosol
created [InstanceEdit:174962] Jassal, B, 2006-02-23 11:52:06
input [DefinedSet:174971] NAT2 substrate [cytosol] [EntityWithAccessionedSequence:158833] AcC-NAT2 [cytosol] [Homo sapiens]
literatureReference [LiteratureReference:8984625] Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases [LiteratureReference:8984641] N-acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: enzymology and bioactivation [LiteratureReference:8984671] Arylamine N-acetyltransferases: a structural perspective
modified [InstanceEdit:176096] Jassal, B, 2006-03-03 14:54:21 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:177810] D'Eustachio, P, 2006-04-07 13:51:03 [InstanceEdit:353652] Jassal, Bijay, 2008-06-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8984615] Duenas, Corina, 2017-04-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name NAT2 acetylation
output [DefinedSet:174958] NAT2 acetylated conjugate [cytosol] [EntityWithAccessionedSequence:158692] NAT2 [cytosol] [Homo sapiens]
precedingEvent
releaseDate 2005-09-26
reviewed [InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:358221] R-HSA-174967.4
summation [Summation:176095] Typical NAT 2 substrates were chosen as examples. They are p...
(hasEvent) [Pathway:156582] Acetylation [Homo sapiens]
(precedingEvent) [Reaction:158832] The acetyl group from acetyl-CoA is transferred to NAT2 [Homo sapiens]
(updatedInstance) [_UpdateTracker:9781440] Update Tracker - [Reaction:174967] NAT2 acetylation - v61:[addLiteratureReference]
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No pathways have been reviewed or authored by NAT2 acetylation (174967)