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Details on Person RFC dissociates after sliding clamp formation on the C-strand of the telomere

Class:IdReaction:174447
_displayNameRFC dissociates after sliding clamp formation on the C-strand of the telomere
_doReleaseTRUE
_timestamp2020-05-04 11:31:00
authored[InstanceEdit:176728] Blackburn, EH, Seidel, J, 2006-03-09 19:41:08
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:174443] Gillespie, ME, 2006-02-17 20:47:42
edited[InstanceEdit:9686480] Orlic-Milacic, Marija, 2020-05-04
goBiologicalProcess[GO_BiologicalProcess:263978] telomere maintenance via semi-conservative replication
input[Complex:174449] RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:69070] Replication factor C disengages from proliferating cell nuclear antigen (PCNA) upon sliding clamp formation, and PCNA itself tethers DNA polymerase delta to DNA.
modified[InstanceEdit:176720] Gillespie, ME, 2006-03-09 16:26:41
[InstanceEdit:176727] Gillespie, ME, 2006-03-09 19:06:16
[InstanceEdit:176736] Gillespie, ME, 2006-03-09 19:42:21
[InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11
[InstanceEdit:177977] Gillespie, ME, 2006-04-13 15:15:41
[InstanceEdit:180785] Gillespie, ME, 2006-06-05 04:16:53
[InstanceEdit:182677] Gopinathrao, G, 2006-07-12 03:00:19
[InstanceEdit:182787] Gillespie, ME, 2006-07-13 18:34:39
[InstanceEdit:183139] Gillespie, ME, 2006-07-21 18:01:36
[InstanceEdit:183145] Gillespie, ME, 2006-07-21 18:37:18
[InstanceEdit:183148] Gopinathrao, G, 2006-07-24 03:46:25
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:8981644] D'Eustachio, Peter, 2017-03-13
[InstanceEdit:9668889] Orlic-Milacic, Marija, 2019-12-01
[InstanceEdit:9668890] Orlic-Milacic, Marija, 2019-12-01
[InstanceEdit:9676315] Orlic-Milacic, Marija, 2020-02-12
[InstanceEdit:9676316] Orlic-Milacic, Marija, 2020-02-12
[InstanceEdit:9686483] Orlic-Milacic, Marija, 2020-05-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRFC dissociates after sliding clamp formation on the C-strand of the telomere
output[Complex:174450] RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] [Homo sapiens]
[CandidateSet:9668941] RFC,(CFT18-RFC) [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2005-09-26
reviewed[InstanceEdit:182786] Price, C, 2006-07-13 18:33:38
[InstanceEdit:9672970] Gillespie, Marc E, 2020-01-03
[InstanceEdit:9686481] Hayashi, Makoto T, 2020-04-29
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:9671059] Orlic-Milacic, Marija, 2019-12-18
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359441] R-HSA-174447.6
summation[Summation:69069] It is assumed that, as shown for generic DNA replication (Po...
(hasEvent)[Pathway:174411] Polymerase switching on the C-strand of the telomere [Homo sapiens]
(precedingEvent)[Reaction:174448] Formation of Processive Complex on the C-strand of the telomere [Homo sapiens]
[NegativePrecedingEvent:9766493] Futile Cycle: RFC dissociates after sliding clamp formation on the C-strand of the telomere
(updatedInstance)[_UpdateTracker:9776979] Update Tracker - [Reaction:174447] RFC dissociates after sliding clamp formation on the C-strand of the telomere - v73:[modifyText]
[_UpdateTracker:9777376] Update Tracker - [Reaction:174447] RFC dissociates after sliding clamp formation on the C-strand of the telomere - v72:[addLiteratureReference, add_removeOutput, modifyText]
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