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Details on Person Removal of remaining Flap from the C-strand
Class:Id Reaction:174446 _displayName Removal of remaining Flap from the C-strand _doRelease TRUE _timestamp 2020-05-04 11:31:11 authored [InstanceEdit:176728] Blackburn, EH, Seidel, J, 2006-03-09 19:41:08 catalystActivity [CatalystActivity:69151] 5'-flap endonuclease activity of FEN1 [nucleoplasm] compartment [Compartment:7660] nucleoplasm created [InstanceEdit:174443] Gillespie, ME, 2006-02-17 20:47:42 edited [InstanceEdit:9686480] Orlic-Milacic, Marija, 2020-05-04 goBiologicalProcess [GO_BiologicalProcess:263978] telomere maintenance via semi-conservative replication input [Complex:174440] Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] [Homo sapiens] literatureReference [LiteratureReference:9668969] The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation [LiteratureReference:9668984] FEN1 ensures telomere stability by facilitating replication fork re-initiation modified [InstanceEdit:176720] Gillespie, ME, 2006-03-09 16:26:41 [InstanceEdit:176727] Gillespie, ME, 2006-03-09 19:06:16 [InstanceEdit:176736] Gillespie, ME, 2006-03-09 19:42:21 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:177977] Gillespie, ME, 2006-04-13 15:15:41 [InstanceEdit:180785] Gillespie, ME, 2006-06-05 04:16:53 [InstanceEdit:182677] Gopinathrao, G, 2006-07-12 03:00:19 [InstanceEdit:182787] Gillespie, ME, 2006-07-13 18:34:39 [InstanceEdit:183139] Gillespie, ME, 2006-07-21 18:01:36 [InstanceEdit:183145] Gillespie, ME, 2006-07-21 18:37:18 [InstanceEdit:183148] Gopinathrao, G, 2006-07-24 03:46:25 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8981644] D'Eustachio, Peter, 2017-03-13 [InstanceEdit:9668980] Orlic-Milacic, Marija, 2019-12-02 [InstanceEdit:9668989] Orlic-Milacic, Marija, 2019-12-02 [InstanceEdit:9686483] Orlic-Milacic, Marija, 2020-05-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name Removal of remaining Flap from the C-strand output [Complex:174432] Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] [Homo sapiens] precedingEvent
regulatedBy [PositiveRegulation:9668978] Positive regulation by 'WRN [nucleoplasm]' releaseDate 2006-08-02 reviewed [InstanceEdit:182786] Price, C, 2006-07-13 18:33:38 [InstanceEdit:9686481] Hayashi, Makoto T, 2020-04-29 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:358580] R-HSA-174446.6 summation [Summation:9668977] The remaining flap, which is too short to support RPA bindin... (hasEvent) [Pathway:174437] Removal of the Flap Intermediate from the C-strand [Homo sapiens] (precedingEvent) [Reaction:174456] Joining of adjacent Okazaki fragments of the C-strand [Homo sapiens] (updatedInstance) [_UpdateTracker:9777210] Update Tracker - [Reaction:174446] Removal of remaining Flap from the C-strand - v72:[addLiteratureReference, addRegulator, add_removeSummation] [_UpdateTracker:9788751] Update Tracker - [Reaction:174446] Removal of remaining Flap from the C-strand - v40:[modifyText]
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