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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person HCYS [cytosol]

Class:IdSimpleEntity:174369
_displayNameHCYS [cytosol]
_timestamp2024-04-19 21:20:51
compartment[Compartment:70101] cytosol
created[InstanceEdit:174378] Jassal, Bijay, 2006-02-17
modified[InstanceEdit:2537470] Wu, G, 2012-10-26
[InstanceEdit:9616752] Shorser, Solomon, 2018-08-13
[InstanceEdit:9619952] Wu, G, 2018-09-19
[InstanceEdit:9759628] D'Eustachio, Peter, 2021-12-08
[InstanceEdit:9908226] D'Eustachio, Peter, 2024-04-19
[InstanceEdit:9989189] Weiser, Joel, 2026-05-17
nameHCYS
L-homocysteine zwitterion
homocysteine
homocysteine zwitterion
referenceEntity[ReferenceMolecule:9908225] L-homocysteine zwitterion [ChEBI:58199]
stableIdentifier[StableIdentifier:368907] R-ALL-174369.5
(input)[Reaction:174374] MTR transfers CH3 from MeCbl to HCYS [Homo sapiens]
[Reaction:1614524] PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine [Homo sapiens]
[Reaction:1614567] Excess homocysteine yields homolanthionine and H2S [Homo sapiens]
[Reaction:1614631] Homocysteine is degraded to oxobutanoate and H2S [Homo sapiens]
[Reaction:1614654] BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY [Homo sapiens]
[FailedReaction:3322140] Defective MTR does not transfer CH3 group from MeCbl to HCYS [Homo sapiens]
[Reaction:5696838] BHMT2 tetramer transfers CH3 group from SMM to LHCYS [Homo sapiens]
(output)[Reaction:174401] AHCY:NAD+ tetramer hydrolyses AdoHcy [Homo sapiens]
[Reaction:379464] COMT transfers Met to DOPAC to form HVA [Homo sapiens]
(regulator)[PositiveRegulation:1655890] Positive regulation by 'HCYS [cytosol]'
(updatedInstance)[_UpdateTracker:9874215] Update Tracker - [SimpleEntity:174369] HCYS [cytosol] - v43:[addName]
[_UpdateTracker:9889935] Update Tracker - [SimpleEntity:174369] HCYS [cytosol] - v52:[modifyName]
[_UpdateTracker:9903083] Update Tracker - [SimpleEntity:174369] HCYS [cytosol] - v80:[addName, add_removeReferenceEntity]
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No pathways have been reviewed or authored by HCYS [cytosol] (174369)
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