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Details on Person SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen

Class:IdReaction:174368
_displayNameSLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen
_doReleaseTRUE
_timestamp2014-07-01 12:31:32
authored[InstanceEdit:174378] Jassal, Bijay, 2006-02-17
catalystActivity[CatalystActivity:174365] UDP-glucuronate transmembrane transporter activity of SLC35D1 hexamer [endoplasmic reticulum membrane]
compartment[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:174378] Jassal, Bijay, 2006-02-17
edited[InstanceEdit:174378] Jassal, Bijay, 2006-02-17
input[SimpleEntity:158601] UDP-GlcA [cytosol]
[SimpleEntity:162756] UDP-GlcNAc [cytosol]
literatureReference[LiteratureReference:266240] Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity
modified[InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11
[InstanceEdit:266244] Jassal, Bijay, 2008-04-29
[InstanceEdit:353652] Jassal, Bijay, 2008-06-13
[InstanceEdit:762750] Jassal, Bijay, 2010-05-20
[InstanceEdit:762751] Jassal, Bijay, 2010-05-20
[InstanceEdit:3499325] Jassal, Bijay, 2013-05-17
[InstanceEdit:3903036] Jassal, Bijay, 2013-07-17
[InstanceEdit:5603295] Jassal, Bijay, 2014-07-01
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen
output[SimpleEntity:174384] UDP-GlcA [endoplasmic reticulum lumen]
[SimpleEntity:3499326] UDP-GlcNAc [endoplasmic reticulum lumen]
precedingEvent
releaseDate2010-06-15
reviewed[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5603195] Jassal, Bijay, 2014-06-30
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361013] R-HSA-174368.2
summation[Summation:179287] The UDP-glucuronic acid/UDP-N-acetylgalactosamine transporte...
(hasEvent)[Pathway:173599] Formation of the active cofactor, UDP-glucuronate [Homo sapiens]
[Pathway:727802] Transport of nucleotide sugars [Homo sapiens]
(inferredFrom)[Reaction:9912889] SLC35D2 exchanges UDP-GlcA for UMP [Homo sapiens]
(normalReaction)[FailedReaction:5603297] Defective SLC35D1 does not transport UDP-GlcA, UDPGlcNAc [Homo sapiens]
(precedingEvent)[Reaction:159179] UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG [Homo sapiens]
[Reaction:159194] UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG [Homo sapiens]
[Reaction:159289] 6-dehydrotestosterone can form an O-glucuronide [Homo sapiens]
[Reaction:174916] Formation of N-glucuronides [Homo sapiens]
[Reaction:174931] UGTs transfer GlcA from UDP-GlcA to O-centre substrates [Homo sapiens]
[Reaction:9632038] UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG [Homo sapiens]
[Reaction:9632039] UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785013] Update Tracker - [Reaction:174368] SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen - v52:[modifyText]
[_UpdateTracker:9785967] Update Tracker - [Reaction:174368] SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen - v50:[modifyText]
[_UpdateTracker:9787115] Update Tracker - [Reaction:174368] SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen - v46:[add_removeInput]
[_UpdateTracker:9787353] Update Tracker - [Reaction:174368] SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen - v45:[addInput, addOutput, modifyText]
[_UpdateTracker:9790588] Update Tracker - [Reaction:174368] SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen - v33:[modifyText]
[_UpdateTracker:9791899] Update Tracker - [Reaction:174368] SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen - v25:[addLiteratureReference, modifyText]
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