Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person GCL ligates L-Glu to L-Cys
Class:Id Reaction:174367 _displayName GCL ligates L-Glu to L-Cys _doRelease TRUE _timestamp 2021-09-20 12:18:18 authored [InstanceEdit:174378] Jassal, Bijay, 2006-02-17 catalystActivity [CatalystActivity:174398] glutamate-cysteine ligase activity of GCL [cytosol] compartment [Compartment:70101] cytosol created [InstanceEdit:174378] Jassal, Bijay, 2006-02-17 edited [InstanceEdit:1247945] Jassal, B, 2011-04-08 input [SimpleEntity:29404] L-Glu [cytosol] [SimpleEntity:111707] L-Cys [cytosol] [SimpleEntity:113592] ATP [cytosol] literatureReference [LiteratureReference:1247938] Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues [LiteratureReference:1247925] Expression and purification of human gamma-glutamylcysteine synthetase modified [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:353652] Jassal, Bijay, 2008-06-13 [InstanceEdit:1247945] Jassal, B, 2011-04-08 [InstanceEdit:1250388] Jassal, B, 2011-04-19 [InstanceEdit:5602968] Jassal, Bijay, 2014-06-25 [InstanceEdit:5633399] Matthews, Lisa, 2014-10-31 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9753919] Jassal, Bijay, 2021-09-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name GCL ligates L-Glu to L-Cys output [SimpleEntity:174393] gGluCys [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29372] Pi [cytosol] precedingEvent
releaseDate 2005-06-13 reviewed [InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54 reviewStatus [ReviewStatus:9821382] five stars revised [InstanceEdit:5602271] Jassal, Bijay, 2014-06-23 species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:358834] R-HSA-174367.4 summation [Summation:178811] The first step in the formation of glutathione is the ligati... systematicName GCL ligates L-Glu, L-Cys to gGluCys (hasEvent) [Pathway:174403] Glutathione synthesis and recycling [Homo sapiens] (normalReaction) [FailedReaction:5602892] Defective GCLC does not ligate L-Glu to L-Cys [Homo sapiens] (precedingEvent) [Reaction:174394] GSS:Mg2+ dimer synthesizes GSH [Homo sapiens] [Reaction:1247922] GGCT transforms gGluCys to OPRO [Homo sapiens] (updatedInstance) [_UpdateTracker:9786137] Update Tracker - [Reaction:174367] GCL ligates L-Glu to L-Cys - v50:[modifyText] [_UpdateTracker:9789690] Update Tracker - [Reaction:174367] GCL ligates L-Glu to L-Cys - v37:[addLiteratureReference, modifyText]
[Change default viewing format]
List...
Protein identifiers
ChEBI identifiers
KEGG COMPOUND identifiers
No pathways have been reviewed or authored by GCL ligates L-Glu to L-Cys (174367)
