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Details on Person Degradation of multiubiquitinated Securin

Class:IdBlackBoxEvent:174202
_displayNameDegradation of multiubiquitinated Securin
_doReleaseTRUE
_timestamp2016-11-10 00:56:04
authored[InstanceEdit:174241] Lorca, T, Castro, A, 2006-01-26 00:00:00
catalystActivity[CatalystActivity:68824] endopeptidase activity of 26S proteasome [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:174149] Matthews, L, 2006-02-17 00:41:48
edited[InstanceEdit:174183] Matthews, L, 2006-01-30 00:00:00
input[Complex:3095944] CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:174096] Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1
modified[InstanceEdit:176825] Matthews, L, 2006-03-13 00:07:09
[InstanceEdit:176927] Matthews, L, 2006-03-16 21:33:00
[InstanceEdit:177346] Matthews, L, 2006-03-28 00:21:29
[InstanceEdit:194433] Schmidt, EE, 2007-03-13 12:36:50
[InstanceEdit:3095942] D'Eustachio, P, 2013-02-08
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDegradation of multiubiquitinated Securin
output[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[Complex:174081] CDC20:p-APC/C [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
precedingEvent
releaseDate2005-06-13
reviewed[InstanceEdit:177300] Peters, JM, 2006-03-27 22:55:09
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361629] R-HSA-174202.3
summation[Summation:176899] Following ubiquitination, securin is degraded by the 26S pro...
(hasEvent)[Pathway:174154] APC/C:Cdc20 mediated degradation of Securin [Homo sapiens]
[Pathway:2467813] Separation of Sister Chromatids [Homo sapiens]
(precedingEvent)[NegativePrecedingEvent:9764069] Futile Cycle: Degradation of multiubiquitinated Securin
[NegativePrecedingEvent:9764071] Futile Cycle: Degradation of multiubiquitinated Securin
[NegativePrecedingEvent:9764102] Futile Cycle: Degradation of multiubiquitinated Securin
[NegativePrecedingEvent:9764104] Futile Cycle: Degradation of multiubiquitinated Securin
[NegativePrecedingEvent:9764107] Futile Cycle: Degradation of multiubiquitinated Securin
[NegativePrecedingEvent:9764108] Futile Cycle: Degradation of multiubiquitinated Securin
[NegativePrecedingEvent:9764134] Futile Cycle: Degradation of multiubiquitinated Securin
[NegativePrecedingEvent:9764138] Futile Cycle: Degradation of multiubiquitinated Securin
[Reaction:174224] Dissociation of Cdc20 from APC/C complex [Homo sapiens]
[Reaction:2467775] Autocleavage of ESPL1 (Separase) [Homo sapiens]
(updatedInstance)[_UpdateTracker:9788033] Update Tracker - [BlackBoxEvent:174202] Degradation of multiubiquitinated Securin - v44:[add_removeInput]
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