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Details on Person Ubiquitination of Emi1 by SCF-beta-TrCP

Class:IdReaction:174159
_displayNameUbiquitination of Emi1 by SCF-beta-TrCP
_doReleaseTRUE
_timestamp2022-02-08 22:53:09
authored[InstanceEdit:174241] Lorca, T, Castro, A, 2006-01-26 00:00:00
catalystActivity[CatalystActivity:9764127] ubiquitin-protein transferase activity of SCF-beta-TrCP:phospho-Emi1 complexes [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:174149] Matthews, L, 2006-02-17 00:41:48
edited[InstanceEdit:174183] Matthews, L, 2006-01-30 00:00:00
input[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[Complex:174138] SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:163011] Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1
modified[InstanceEdit:176467] Matthews, L, 2006-03-07 23:53:01
[InstanceEdit:177375] Matthews, L, 2006-03-28 00:29:57
[InstanceEdit:178124] Matthews, L, 2006-04-17 21:07:47
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9764086] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9764098] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9764110] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9764129] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9764136] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameUbiquitination of Emi1 by SCF-beta-TrCP
negativePrecedingEvent[NegativePrecedingEvent:9764076] Futile Cycle: Degradation multiubiquitinated Cyclin A
[NegativePrecedingEvent:9764091] Futile Cycle: Degradation of multiubiquitinated Cyclin B
[NegativePrecedingEvent:9764089] Futile Cycle: Degradation of multiubiquitinated Nek2A
[NegativePrecedingEvent:9764108] Futile Cycle: Degradation of multiubiquitinated Securin
[NegativePrecedingEvent:9764109] Futile Cycle: Degradation of multiubiquitinated cell cycle proteins
[NegativePrecedingEvent:9764132] Futile Cycle: SCF-mediated degradation of Emi1
output[Complex:174061] SCF-associated multiubiquitinated Emi1complexes [cytosol] [Homo sapiens]
precedingEvent
releaseDate2005-04-11
reviewed[InstanceEdit:177300] Peters, JM, 2006-03-27 22:55:09
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358531] R-HSA-174159.4
summation[Summation:176422] Following its association with SCF-ßTrCP, phospho-Emi1 is po...
(hasEvent)[Pathway:174113] SCF-beta-TrCP mediated degradation of Emi1 [Homo sapiens]
(precedingEvent)[BlackBoxEvent:174203] SCF-mediated degradation of Emi1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9774875] Update Tracker - [Reaction:174159] Ubiquitination of Emi1 by SCF-beta-TrCP - v80:[add_removeCatalystActivity]
[_UpdateTracker:9782251] Update Tracker - [Reaction:174159] Ubiquitination of Emi1 by SCF-beta-TrCP - v59:[modifyText]
[_UpdateTracker:9789825] Update Tracker - [Reaction:174159] Ubiquitination of Emi1 by SCF-beta-TrCP - v37:[modifyText]
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