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Details on Person Ubiquitination of Securin by phospho-APC/C:Cdc20 complex
Class:Id Reaction:174144 _displayName Ubiquitination of Securin by phospho-APC/C:Cdc20 complex _doRelease TRUE _timestamp 2022-02-08 22:53:12 authored [InstanceEdit:174241] Lorca, T, Castro, A, 2006-01-26 00:00:00 catalystActivity [CatalystActivity:9764123] ubiquitin-protein transferase activity of CDC20:p-APC/C:PTTG1 [cytosol] compartment [Compartment:70101] cytosol created [InstanceEdit:174149] Matthews, L, 2006-02-17 00:41:48 edited [InstanceEdit:174183] Matthews, L, 2006-01-30 00:00:00 goBiologicalProcess [GO_BiologicalProcess:7441] ubiquitin-dependent protein catabolic process input [DefinedSet:113595] Ub [cytosol] [Homo sapiens] [DefinedSet:113595] Ub [cytosol] [Homo sapiens] [DefinedSet:113595] Ub [cytosol] [Homo sapiens] [Complex:174212] CDC20:p-APC/C:PTTG1 [cytosol] [Homo sapiens] literatureReference [LiteratureReference:174096] Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1 [LiteratureReference:976062] Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex modified [InstanceEdit:176939] Matthews, L, 2006-03-16 21:36:14 [InstanceEdit:177376] Matthews, L, 2006-03-28 00:30:10 [InstanceEdit:177822] Matthews, L, 2006-04-09 23:12:52 [InstanceEdit:177824] Matthews, L, 2006-04-10 08:37:24 [InstanceEdit:186981] Matthews, L, 2006-09-05 23:28:03 [InstanceEdit:3095942] D'Eustachio, P, 2013-02-08 [InstanceEdit:3162920] D'Eustachio, P, 2013-02-20 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9764075] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9764086] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9764098] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9764110] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9764118] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9764126] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9764136] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name Ubiquitination of Securin by phospho-APC/C:Cdc20 complex negativePrecedingEvent [NegativePrecedingEvent:9764069] Futile Cycle: Degradation of multiubiquitinated Securin [NegativePrecedingEvent:9764080] Futile Cycle: Degradation multiubiquitinated Cyclin A [NegativePrecedingEvent:9764093] Futile Cycle: Degradation of multiubiquitinated Nek2A [NegativePrecedingEvent:9764105] Futile Cycle: Degradation of multiubiquitinated cell cycle proteins [NegativePrecedingEvent:9764113] Futile Cycle: SCF-mediated degradation of Emi1 [NegativePrecedingEvent:9764133] Futile Cycle: Degradation of multiubiquitinated Cyclin B output [Complex:3095944] CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] [Homo sapiens] precedingEvent
releaseDate 2005-06-13 reviewed [InstanceEdit:177300] Peters, JM, 2006-03-27 22:55:09 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:361077] R-HSA-174144.4 summation [Summation:176912] Securin is ubiquitinated by APC/C:Cdc20 (Hagting et al., 200... (hasEvent) [Pathway:174154] APC/C:Cdc20 mediated degradation of Securin [Homo sapiens] [Pathway:2467813] Separation of Sister Chromatids [Homo sapiens] (precedingEvent) [BlackBoxEvent:174202] Degradation of multiubiquitinated Securin [Homo sapiens] (updatedInstance) [_UpdateTracker:9774880] Update Tracker - [Reaction:174144] Ubiquitination of Securin by phospho-APC/C:Cdc20 complex - v80:[add_removeCatalystActivity] [_UpdateTracker:9787651] Update Tracker - [Reaction:174144] Ubiquitination of Securin by phospho-APC/C:Cdc20 complex - v44:[addLiteratureReference, add_removeOutput, modifyText]
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