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Details on Person RT [cytosol]

Class:Id	Complex:173772
_displayName	RT [cytosol]
_timestamp	2013-01-29 21:35:19
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:173765] Gopinathrao, G, 2006-02-16 23:18:33
hasComponent	[EntityWithAccessionedSequence:173834] p51 (RT) [cytosol] [Human immunodeficiency virus 1] [EntityWithAccessionedSequence:173370] Reverse transcriptase/ribonuclease H [cytosol] [Human immunodeficiency virus 1]
modified	[InstanceEdit:175576] Gopinathrao, G, 2006-02-23 23:50:37 [InstanceEdit:2167930] D'Eustachio, P, 2012-03-23 [InstanceEdit:2169052] D'Eustachio, P, 2012-03-27 [InstanceEdit:3006294] Gillespie, ME, 2013-01-29
name	RT Reverse Transcriptase heterodimer
species	[Species:164493] Human immunodeficiency virus 1
stableIdentifier	[StableIdentifier:369882] R-HIV-173772.1
(activeUnit)	[CatalystActivity:173770] RNA-DNA hybrid ribonuclease activity of RTC with minus strand DNA synthesis initiated from 3'-end [cytosol] [CatalystActivity:173775] DNA-directed DNA polymerase activity of RTC with annealed complementary PBS seqments in +sssDNA and -strand DNA [cytosol] [CatalystActivity:173777] RNA-directed DNA polymerase activity of RTC with minus sssDNA transferred to 3'-end of viral RNA template [cytosol] [CatalystActivity:173785] RNA-DNA hybrid ribonuclease activity of RTC with minus sssDNA:tRNA primer:RNA template [cytosol] [CatalystActivity:173806] RNA-directed DNA polymerase activity of RTC with tRNA primer:RNA template [cytosol] [CatalystActivity:173811] DNA-directed DNA polymerase activity of RTC with extending minus strand DNA [cytosol] [CatalystActivity:173828] DNA-directed DNA polymerase activity of RTC without viral RNA template [cytosol] [CatalystActivity:182888] RNA-DNA hybrid ribonuclease activity of RTC with extensive RNase-H digestion [cytosol] [CatalystActivity:182891] RNA-DNA hybrid ribonuclease activity of RTC with extending second-strand DNA [cytosol]
(hasComponent)	[Complex:173653] uncoated viral complex [cytosol] [Homo sapiens] [Complex:173659] duplicate Encapsidated viral core [cytosol] [Human immunodeficiency virus 1] [Complex:173664] Viral core surrounded by Matrix layer [cytosol] [Homo sapiens] [Complex:173764] RTC with extending minus strand DNA [cytosol] [Homo sapiens] [Complex:173773] RTC with degraded RNA template and minus sssDNA [cytosol] [Homo sapiens] [Complex:173774] RTC with minus sssDNA:tRNA primer:RNA template [cytosol] [Homo sapiens] [Complex:173779] RTC with minus sssDNA transferred to 3'-end of viral RNA template [cytosol] [Homo sapiens] [Complex:173786] RTC with minus strand DNA synthesis initiated from 3'-end [cytosol] [Homo sapiens] [Complex:173789] RTC with extensive RNase-H digestion [cytosol] [Homo sapiens] [Complex:173792] RTC with annealed complementary PBS seqments in +sssDNA and -strand DNA [cytosol] [Homo sapiens] List all 20 refering instances
(output)	[Reaction:173115] Formation of Pre-Integration Complex (PIC) [Homo sapiens]
(physicalEntity)	[CatalystActivity:182837] RNA-DNA hybrid ribonuclease activity of RT [cytosol]
(updatedInstance)	[_UpdateTracker:9867600] Update Tracker - [Complex:173772] RT [cytosol] - v25:[updateContainedComponent] [_UpdateTracker:9878001] Update Tracker - [Complex:173772] RT [cytosol] - v44:[add_removeHasComponent]
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No pathways have been reviewed or authored by RT [cytosol] (173772)