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Details on Person p-2S-SMAD2,3:SMAD4 [nucleoplasm]

Class:IdDefinedSet:173511
_displayNamep-2S-SMAD2,3:SMAD4 [nucleoplasm]
_timestamp2021-07-15 12:59:37
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:173513] Jassal, B, 2006-02-10 14:02:35
hasMember
modified[InstanceEdit:176038] Jassal, B, 2006-03-01 09:49:08
[InstanceEdit:177100] Jassal, B, 2006-03-22 11:41:32
[InstanceEdit:179506] Schmidt, EE, 2006-05-05 07:05:29
[InstanceEdit:1484110] Orlic-Milacic, Marija, 2011-08-12
[InstanceEdit:1530047] Orlic-Milacic, Marija, 2011-08-25
[InstanceEdit:1567610] Jassal, B, 2011-09-06
[InstanceEdit:1584600] Jassal, B, 2011-09-08
[InstanceEdit:9736934] Orlic-Milacic, Marija, 2021-07-15
[InstanceEdit:9736935] Orlic-Milacic, Marija, 2021-07-15
namep-2S-SMAD2,3:SMAD4
Phospho-R-SMAD:CO-SMAD complex
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:363066] R-HSA-173511.2
(activeUnit)[PositiveGeneExpressionRegulation:2187299] Positive gene expression regulation by 'p-2S-SMAD2,3:SMAD4:JUNB gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:9625537] Positive gene expression regulation by 'FOXO1:p-2S-SMAD2/3:SMAD4:MSTN gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:9625768] Positive gene expression regulation by 'FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:TRIM63 gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:9733201] Positive gene expression regulation by 'p-2S-SMAD2,3:SMAD4 [nucleoplasm]'
(hasComponent)[Complex:177110] p-2S-SMAD2,3:SMAD4:SKI/SKIL:NCOR [nucleoplasm] [Homo sapiens]
[Complex:870446] p-SMAD2,3:SMAD4:TRIM33 [nucleoplasm] [Homo sapiens]
[Complex:1225870] SMAD2,3:SMAD4:FOXH1:Activin Response Element [nucleoplasm] [Homo sapiens]
[Complex:1535906] SMAD2,3:SMAD4:FOXO3:FoxO3a-binding Element [nucleoplasm] [Homo sapiens]
[Complex:2106580] WWTR1:p-2S-SMAD2,3:SMAD4 [nucleoplasm] [Homo sapiens]
[Complex:2127250] p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 [nucleoplasm] [Homo sapiens]
[Complex:2167877] p-SMAD2/3:Ub-SMAD4 [nucleoplasm] [Homo sapiens]
[Complex:2186606] p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] [Homo sapiens]
[Complex:2186642] p-2S-SMAD2,3:SMAD4:MEN1 [nucleoplasm] [Homo sapiens]
[Complex:2187302] p-2S-SMAD2,3:SMAD4:SP1 [nucleoplasm] [Homo sapiens]
List all 29 refering instances
(input)[Reaction:173481] SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling [Homo sapiens]
[BlackBoxEvent:173545] Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling [Homo sapiens]
[Reaction:870538] TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus [Homo sapiens]
[Reaction:1225919] Phospho R-SMAD(SMAD2,3):CO-SMAD(SMAD4):FOXH1 binds Activin Response Element [Homo sapiens]
[Reaction:1535903] Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements [Homo sapiens]
[Reaction:2127257] SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 [Homo sapiens]
[Reaction:2176475] Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 [Homo sapiens]
[Reaction:2186607] TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer [Homo sapiens]
[Reaction:2186643] MEN1 binds SMAD2/3:SMAD4 heterotrimer [Homo sapiens]
[Reaction:2187309] SMAD2/3:SMAD4 heterotrimer binds SP1 [Homo sapiens]
List all 33 refering instances
(output)[BlackBoxEvent:173488] The SMAD2/3:SMAD4 complex transfers to the nucleus [Homo sapiens]
[Reaction:2186747] Ubiquitination of SKI/SKIL by RNF111/SMURF2 [Homo sapiens]
[Reaction:2186755] Ubiquitination of SKI/SKIL by Rnf111 [Homo sapiens]
[BlackBoxEvent:9846551] GOCAM The SMAD2/3:SMAD4 complex transfers to the nucleus [Homo sapiens]
(regulator)[PositiveGeneExpressionRegulation:9733201] Positive gene expression regulation by 'p-2S-SMAD2,3:SMAD4 [nucleoplasm]'
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No pathways have been reviewed or authored by p-2S-SMAD2,3:SMAD4 [nucleoplasm] (173511)
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