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Details on Person Formation of Pre-Integration Complex (PIC)

Class:Id	Reaction:173115
_displayName	Formation of Pre-Integration Complex (PIC)
_doRelease	TRUE
_timestamp	2018-05-15 19:01:28
authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:173116] Gopinathrao, G, 2006-02-07 19:48:25
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
input	[Complex:9608475] RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:175672] Correct integration of retroviral DNA in vitro [LiteratureReference:175524] The barrier-to-autointegration protein is a host factor for HIV type 1 integration [Book:175927] 9780879695712 Integration Retroviruses Coffin, JM [LiteratureReference:177396] Genome-wide analysis of retroviral DNA integration [LiteratureReference:175852] HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro [LiteratureReference:177403] Retroviral DNA integration--mechanism and consequences [LiteratureReference:170601] Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition
modified	[InstanceEdit:174501] Gopinathrao, G, 2006-02-17 21:37:08 [InstanceEdit:175576] Gopinathrao, G, 2006-02-23 23:50:37 [InstanceEdit:175638] Gopinathrao, G, 2006-02-25 14:03:09 [InstanceEdit:176000] Gopinathrao, G, 2006-02-27 15:06:24 [InstanceEdit:176402] Gopinathrao, G, 2006-03-07 21:34:46 [InstanceEdit:176739] Gopinathrao, G, 2006-03-10 15:27:37 [InstanceEdit:176837] Gopinathrao, G, 2006-03-13 20:41:00 [InstanceEdit:177399] Gopinathrao, G, 2006-03-29 16:14:14 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:180083] Gopinathrao, G, 2006-05-16 19:02:00 [InstanceEdit:180396] Gopinathrao, G, 2006-05-18 19:59:47 [InstanceEdit:180402] Gopinathrao, G, 2006-05-18 20:43:08 [InstanceEdit:180418] Gopinathrao, G, 2006-05-19 20:14:07 [InstanceEdit:182878] Gopinathrao, G, 2006-07-19 18:40:54 [InstanceEdit:182890] Gopinathrao, G, 2006-07-20 19:02:21 [InstanceEdit:188431] Gopinathrao, G, 2006-10-12 14:53:00 [InstanceEdit:188941] Gopinathrao, G, 2006-10-30 22:24:14 [InstanceEdit:188963] Gopinathrao, G, 2006-11-01 22:14:37 [InstanceEdit:3004618] Jupe, S, 2013-01-29 [InstanceEdit:3006264] Gillespie, ME, 2013-01-29 [InstanceEdit:3006571] Gillespie, ME, 2013-01-30 [InstanceEdit:3008843] Jassal, B, 2013-02-04 [InstanceEdit:3632906] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:8951689] Jupe, Steve, 2016-12-08 [InstanceEdit:9608474] D'Eustachio, Peter, 2018-05-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of Pre-Integration Complex (PIC)
output	[Complex:175143] PIC (PreIntegration Complex) [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:173123] PPIA [cytosol] [Homo sapiens] [Complex:173772] RT [cytosol] [Human immunodeficiency virus 1]
precedingEvent	[Reaction:8951690] Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 [Homo sapiens] [Reaction:182876] Removal of plus-strand flap and gap closure complete synthesis of linear duplex viral DNA [Homo sapiens]
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-11-14
reviewed	[InstanceEdit:188934] Bushman, FD, 2006-10-30 22:19:13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360216] R-HSA-173115.4
summation	[Summation:177409] Concomitant with the completion of reverse transcription, th...
(hasEvent)	[Pathway:162592] Integration of provirus [Homo sapiens]
(precedingEvent)	[Reaction:164514] Integrase binds viral DNA ends [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779545] Update Tracker - [Reaction:173115] Formation of Pre-Integration Complex (PIC) - v65:[add_removeInput] [_UpdateTracker:9781981] Update Tracker - [Reaction:173115] Formation of Pre-Integration Complex (PIC) - v60:[add_removeInput] [_UpdateTracker:9787636] Update Tracker - [Reaction:173115] Formation of Pre-Integration Complex (PIC) - v44:[add_removeInput]
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