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Details on Person p-FRS2:CRKL binds C3G

Class:IdReaction:170978
_displayNamep-FRS2:CRKL binds C3G
_doReleaseTRUE
_timestamp2018-06-05 18:31:53
authored[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
compartment[Compartment:74700] endosome membrane
created[InstanceEdit:170970] Jassal, B, 2006-01-25 09:53:37
edited[InstanceEdit:188340] Jassal, Bijay, 2006-10-10
input[Complex:190081] Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] [Homo sapiens]
[EntityWithAccessionedSequence:913472] RAPGEF1 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:187775] Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk
[LiteratureReference:182068] Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
modified[InstanceEdit:182105] Jassal, Bijay, 2006-07-06
[InstanceEdit:187730] Jassal, Bijay, 2006-09-21
[InstanceEdit:187777] Jassal, B, 2006-09-22 13:26:43
[InstanceEdit:188337] Jassal, Bijay, 2006-10-10
[InstanceEdit:188431] Gopinathrao, G, 2006-10-12 14:53:00
[InstanceEdit:188624] Jassal, Bijay, 2006-10-19
[InstanceEdit:190076] Jassal, B, 2006-12-14 13:53:55
[InstanceEdit:196906] Gopinathrao, G, 2007-04-25 14:54:44
[InstanceEdit:204298] Jassal, Bijay, 2007-11-28
[InstanceEdit:1806830] Jassal, Bijay, 2011-10-24
[InstanceEdit:2018637] Jassal, Bijay, 2011-11-23
[InstanceEdit:3008669] Jassal, B, 2013-02-01
[InstanceEdit:9020600] Jassal, Bijay, 2017-09-08
[InstanceEdit:9610183] Rothfels, Karen, 2018-06-05
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namep-FRS2:CRKL binds C3G
output[Complex:190070] Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] [Homo sapiens]
precedingEvent
releaseDate2007-12-11
reviewed[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359339] R-HSA-170978.4
summation[Summation:187779] Rap guanine nucleotide exchange factor 1 (RAPGEF1, C3G) is a...
(hasEvent)[Pathway:170968] Frs2-mediated activation [Homo sapiens]
(precedingEvent)[Reaction:170979] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9779246] Update Tracker - [Reaction:170978] p-FRS2:CRKL binds C3G - v66:[addLiteratureReference, add_removeInput, modifyText]
[_UpdateTracker:9780393] Update Tracker - [Reaction:170978] p-FRS2:CRKL binds C3G - v63:[modifyText]
[_UpdateTracker:9787864] Update Tracker - [Reaction:170978] p-FRS2:CRKL binds C3G - v44:[add_removeInput]
[_UpdateTracker:9791801] Update Tracker - [Reaction:170978] p-FRS2:CRKL binds C3G - v25:[modifyText]
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No pathways have been reviewed or authored by p-FRS2:CRKL binds C3G (170978)
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