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Details on Person FRS2 [plasma membrane]
Class:Id EntityWithAccessionedSequence:170963
_displayName FRS2 [plasma membrane]
_timestamp 2013-05-24 19:41:35
compartment [Compartment:876] plasma membrane
created [InstanceEdit:170962] Jassal, B, 2006-01-25 09:51:21
endCoordinate 508
modified [InstanceEdit:179505] Schmidt, EE, 2006-05-05 07:02:01 [InstanceEdit:191479] de Bono, B, 2007-01-20 13:35:07 [InstanceEdit:532239] Jupe, S, 2010-02-26 [InstanceEdit:3322333] Wu, G, 2013-05-03 [InstanceEdit:3322334] Wu, G, 2013-05-03 [InstanceEdit:3622465] Rothfels, K, 2013-05-24
name FRS2 FRS2-alpha
referenceEntity [ReferenceGeneProduct:170961] UniProt:Q8WU20 FRS2 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1111792] R-HSA-170963.1
startCoordinate 1
(hasComponent) [Complex:170976] Active TrkA receptor:Frs2 complex [plasma membrane] [Homo sapiens] [Complex:532643] Activated FGFR:FRS2alpha [plasma membrane] [Homo sapiens] [Complex:1982058] Activated FGFR mutants:FRS2 [plasma membrane] [Homo sapiens] [Complex:5654176] Activated FGFR1:FRS2 [plasma membrane] [Homo sapiens] [Complex:5654178] Activated FGFR2:FRS2 [plasma membrane] [Homo sapiens] [Complex:5654180] Activated FGFR3:FRS2 [plasma membrane] [Homo sapiens] [Complex:5654182] Activated FGFR4:FRS2 [plasma membrane] [Homo sapiens] [Complex:5655257] Activated FGFR2 mutants:FRS2 [plasma membrane] [Homo sapiens] [Complex:5655296] Activated FGFR1 mutants:FRS2 [plasma membrane] [Homo sapiens] [Complex:5655299] Activated FGFR4 mutants:FRS2 [plasma membrane] [Homo sapiens]
(hasMember) [DefinedSet:191476] FRS2,3 [plasma membrane] [Homo sapiens] [CandidateSet:9696290] RND2 effectors [cytosol] [Homo sapiens] [CandidateSet:9696296] RND1 effectors [cytosol] [Homo sapiens]
(input) [Reaction:5654399] Activated FGFR2 binds FRS2 [Homo sapiens] [Reaction:5654409] Activated FGFR3 binds FRS2 [Homo sapiens] [Reaction:5654422] Activated FGFR4 binds FRS2 [Homo sapiens] [Reaction:5654569] Activated FGFR1 binds FRS2 [Homo sapiens] [Reaction:5655262] Activated FGFR3 point, translocation and fusion mutants bind FRS2 [Homo sapiens] [Reaction:5655269] Activated FGFR1 mutants bind FRS2 [Homo sapiens] [Reaction:5655339] Activated FGFR2 mutants bind FRS2 [Homo sapiens] [Reaction:5655351] Activated FGFR4 mutants bind FRS2 [Homo sapiens] [Reaction:8855564] 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 [Homo sapiens]
(physicalEntity) [CatalystActivity:170972] transmembrane receptor protein tyrosine kinase adaptor activity of FRS2 [plasma membrane]
(updatedInstance) [_UpdateTracker:9886365] Update Tracker - [EntityWithAccessionedSequence:170963] FRS2 [plasma membrane] - v45:[addName, modifyEndCoordinate]
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Pathways
No pathways have been reviewed or authored by FRS2 [plasma membrane] (170963)