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Details on Person NPC exports GCK1 from nucleus

Class:IdBlackBoxEvent:170825
_displayNameNPC exports GCK1 from nucleus
_doReleaseTRUE
_timestamp2025-08-28 14:42:01
compartment[Compartment:13231] nuclear envelope
created[InstanceEdit:170815] D'Eustachio, P, 2006-01-17 15:36:38
edited[InstanceEdit:174827] D'Eustachio, P, 2006-02-20 18:39:56
goBiologicalProcess[GO_BiologicalProcess:1021] protein export from nucleus
input[EntityWithAccessionedSequence:450102] GCK [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9965335] D'Eustachio, Peter, 2025-08-28
literatureReference[LiteratureReference:170794] Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase
modified[InstanceEdit:174828] D'Eustachio, P, 2006-02-20 18:48:02
[InstanceEdit:177299] D'Eustachio, P, 2006-03-27 19:03:40
[InstanceEdit:450085] D'Eustachio, P, 2009-12-11
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9933517] Stephan, Ralf, 2025-01-01
[InstanceEdit:9939469] Stephan, Ralf, 2025-02-27
[InstanceEdit:9954133] D'Eustachio, Peter, 2025-06-06
[InstanceEdit:9965334] D'Eustachio, Peter, 2025-08-28
[InstanceEdit:9965336] D'Eustachio, Peter, 2025-08-28
[InstanceEdit:9965338] D'Eustachio, Peter, 2025-08-28
nameNPC exports GCK1 from nucleus
glucokinase [nucleoplasm] => glucokinase [cytosol]
output[EntityWithAccessionedSequence:450094] GCK [cytosol] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2005-06-13
reviewed[InstanceEdit:9939470] Matthews, Lisa, 2025-02-27
[InstanceEdit:9965339] Hill, David P, 2025-08-28
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:450087] D'Eustachio, P, 2009-12-11
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359998] R-HSA-170825.6
structureModified[InstanceEdit:9933517] Stephan, Ralf, 2025-01-01
[InstanceEdit:9965334] D'Eustachio, Peter, 2025-08-28
summation[Summation:170823] Free glucokinase (GCK1) leaves the nucleus via the nuclear p...
(hasEvent)[Pathway:170822] Regulation of Glucokinase by Glucokinase Regulatory Protein [Homo sapiens]
(precedingEvent)[Reaction:170824] glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9790913] Update Tracker - [Reaction:170825] glucokinase [nucleoplasm] => glucokinase [cytosol] - v32:[add_removeInput, add_removeOutput, modifyText, removeRegulator]
[_UpdateTracker:9939831] Update Tracker - [BlackBoxEvent:170825] NPC exports GCK1 from nucleus - v92:[removeCatalystActivity]
[_UpdateTracker:9971816] Update Tracker - [BlackBoxEvent:170825] NPC exports GCK1 from nucleus - v95:[addCatalystActivity]
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No pathways have been reviewed or authored by NPC exports GCK1 from nucleus (170825)
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