Query author contributions in Reactome
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Details on Person In the absence of the HIV-1 protein Tat, transcription of th...
| Class:Id | Summation:170741 |
|---|---|
| _displayName | In the absence of the HIV-1 protein Tat, transcription of th... |
| _timestamp | 2006-01-15 13:39:51 |
| created | [InstanceEdit:170768] Matthews, L, 2006-01-15 13:04:15 |
| literatureReference | [LiteratureReference:170634] Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product [LiteratureReference:167724] Tackling Tat |
| modified | [InstanceEdit:170769] Matthews, L, 2006-01-15 13:39:43 |
| text | In the absence of the HIV-1 protein Tat, transcription of the proviral DNA is inefficient and results in the production of truncated transcripts (Kao et al., 1987). While initiation of transcription from the HIV-1 LTR and formation of the early elongation complex occurs normally, transcription elongation is incomplete with non-processive polymerases disengaging from the proviral DNA template prematurely (reviewed in Karn 1999). The mechanism of Tat-mediated elongation is described below. |
| (summation) | [Pathway:167169] HIV Transcription Elongation [Homo sapiens] |
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No pathways have been reviewed or authored by In the absence of the HIV-1 protein Tat, transcription of th... (170741)
