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Details on Person Translocation of active Cdc25C to the nucleus

Class:Id	Reaction:170149
_displayName	Translocation of active Cdc25C to the nucleus
_doRelease	TRUE
_timestamp	2022-02-08 21:42:45
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:170148] Matthews, L, 2005-12-23 13:53:48
input	[EntityWithAccessionedSequence:8981697] p-S198-CDC25C [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:170235] Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C [LiteratureReference:162964] Plk1 promotes nuclear translocation of human Cdc25C during prophase [LiteratureReference:8981695] Differential phosphorylation of Cdc25C phosphatase in mitosis
modified	[InstanceEdit:170184] Matthews, L, 2005-12-28 10:02:46 [InstanceEdit:170263] Matthews, L, 2006-01-04 10:04:54 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8981702] Orlic-Milacic, Marija, 2017-03-13 [InstanceEdit:9764017] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of active Cdc25C to the nucleus
output	[EntityWithAccessionedSequence:156668] p-S198-CDC25C [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:156678] Activation of Cdc25C [Homo sapiens] [BlackBoxEvent:6798268] TP53 and E2F4 inhibit CDC25C expression [Homo sapiens]
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359600] R-HSA-170149.5
summation	[Summation:170241] During interphase, CDC25C, phosphorylated on serine residue ...
(hasEvent)	[Pathway:69273] Cyclin A/B1/B2 associated events during G2/M transition [Homo sapiens]
(precedingEvent)	[Reaction:170153] Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781469] Update Tracker - [Reaction:170149] Translocation of active Cdc25C to the nucleus - v61:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText] [_UpdateTracker:9788754] Update Tracker - [Reaction:170149] Translocation of active Cdc25C to the nucleus - v40:[modifyText]
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No pathways have been reviewed or authored by Translocation of active Cdc25C to the nucleus (170149)