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Details on Person Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes

Class:Id	Reaction:170131
_displayName	Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes
_doRelease	TRUE
_timestamp	2016-11-10 00:55:08
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:170124] Matthews, L, 2005-12-23 13:40:29
input	[Complex:170047] phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:170205] Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal
modified	[InstanceEdit:170184] Matthews, L, 2005-12-28 10:02:46 [InstanceEdit:170638] Matthews, L, 2006-01-09 09:33:11 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes
output	[Complex:170127] phospho-Cyclin B1(CRS):phospho-Cdc2 (Thr 161) [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:170126] Phosphorylation of Cyclin B1 in the CRS domain [Homo sapiens] [Reaction:170076] CAK phosphorylates CDK1 bound to CCNB1 [Homo sapiens] [Reaction:170161] Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B [Homo sapiens] [BlackBoxEvent:4088305] FOXM1 stimulates PLK1 transcription [Homo sapiens]
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359971] R-HSA-170131.3
summation	[Summation:170199] The rapid translocation of cyclin B1:Cdc2 from the cytoplasm...
(hasEvent)	[Pathway:69273] Cyclin A/B1/B2 associated events during G2/M transition [Homo sapiens]
(precedingEvent)	[Reaction:170153] Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases [Homo sapiens]
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No pathways have been reviewed or authored by Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes (170131)