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Details on Person C3G stimulates nucleotide exchange on Rap1

Class:Id	Reaction:169904
_displayName	C3G stimulates nucleotide exchange on Rap1
_doRelease	TRUE
_timestamp	2011-11-04 15:25:14
authored	[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
catalystActivity	[CatalystActivity:169894] guanyl-nucleotide exchange factor activity of Active TrkA receptor:Phospho-ARMS:Crk:C3G complex [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:169892] Jassal, B, 2005-12-16 14:06:36
edited	[InstanceEdit:188340] Jassal, Bijay, 2006-10-10
input	[Complex:169860] Rap1-GDP [cytosol] [Homo sapiens] [SimpleEntity:29438] GTP [cytosol]
literatureReference	[LiteratureReference:182016] Identification of a switch in neurotrophin signaling by selective tyrosine phosphorylation
modified	[InstanceEdit:179398] Jassal, B, 2006-04-21 08:23:16 [InstanceEdit:182105] Jassal, Bijay, 2006-07-06 [InstanceEdit:187064] Jassal, B, 2006-09-08 09:51:14 [InstanceEdit:187773] Jassal, B, 2006-09-21 13:03:02 [InstanceEdit:188337] Jassal, Bijay, 2006-10-10 [InstanceEdit:188431] Gopinathrao, G, 2006-10-12 14:53:00 [InstanceEdit:188620] Jassal, Bijay, 2006-10-19 [InstanceEdit:190210] Jassal, B, 2006-12-18 11:48:10 [InstanceEdit:196906] Gopinathrao, G, 2007-04-25 14:54:44 [InstanceEdit:204298] Jassal, Bijay, 2007-11-28 [InstanceEdit:1806830] Jassal, Bijay, 2011-10-24 [InstanceEdit:1972372] Jassal, B, 2011-11-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	C3G stimulates nucleotide exchange on Rap1
output	[SimpleEntity:29420] GDP [cytosol] [Complex:169866] Rap1-GTP [cytosol] [Homo sapiens]
precedingEvent	[Reaction:169895] Crk's SH3 domain engages C3G [Homo sapiens] [Reaction:169905] ARMS is phosphorylated by active TrkA receptor [Homo sapiens]
releaseDate	2007-12-11
reviewed	[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360918] R-HSA-169904.2
summation	[Summation:187780] Rap1 is a small G protein, necessary for prolonged ERK activ...
(hasEvent)	[Pathway:170984] ARMS-mediated activation [Homo sapiens]
(precedingEvent)	[Reaction:169901] Rap1-GTP complex binds BRAF complex [Homo sapiens]
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No pathways have been reviewed or authored by C3G stimulates nucleotide exchange on Rap1 (169904)