Query author contributions in Reactome
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Details on Person The PLC-gamma 1 docking site in Trk receptor (Y785) is impor...
| Class:Id | Summation:169701 |
|---|---|
| _displayName | The PLC-gamma 1 docking site in Trk receptor (Y785) is impor... |
| _timestamp | 2006-12-07 09:11:17 |
| created | [InstanceEdit:169684] Jassal, Bijay, 2005-11-30 |
| modified | [InstanceEdit:189835] Jassal, Bijay, 2006-12-07 |
| text | The PLC-gamma 1 docking site in Trk receptor (Y785) is important for initiation and maintenance of hippocampal LTP (long term potentiation); this residue in TrkA receptor also binds to CHK tyrosine kinase, which participates in MAPK pathway activation and is involved in PC12 cells neurite outgrowth in response to NGF. PLC-gamma 1 activation results in long term induction of a sodium channel gene (PN1). |
| (summation) | [Reaction:167674] Binding of PLCG1 to active TrkA receptor [Homo sapiens] |
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No pathways have been reviewed or authored by The PLC-gamma 1 docking site in Trk receptor (Y785) is impor... (169701)
