Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person Mcm8 is related to the Mcm2-7 helicase and is found in verte...
| Class:Id | Summation:169442 |
|---|---|
| _displayName | Mcm8 is related to the Mcm2-7 helicase and is found in verte... |
| _timestamp | 2005-11-29 20:49:02 |
| created | [InstanceEdit:169437] Gopinathrao, G, 2005-11-29 15:17:23 |
| modified | [InstanceEdit:169495] Gopinathrao, G, 2005-11-29 20:48:39 |
| text | Mcm8 is related to the Mcm2-7 helicase and is found in vertebrates but not in C. elegans or the yeasts. Studies in Xenopus egg extracts showed that Mcm8 does not associate with the soluble Mcm2-7 complex and binds chromatin upon initiation of DNA synthesis. Mcm8 depletion does not affect replication licensing or Mcm3 loading but slows down DNA synthesis and reduces chromatin recruitment of Rpa34 and DNA polymerase-alpha. Recombinant Mcm8 has ATPase and helicase activities. |
| (summation) | [Reaction:169440] Xenopus Mcm8 mediated fork unwinding [Xenopus laevis] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Mcm8 is related to the Mcm2-7 helicase and is found in verte... (169442)
