Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person TLR6:TLR2 is recruited to ligand:CD14:CD36
Class:Id Reaction:168950
_displayName TLR6:TLR2 is recruited to ligand:CD14:CD36
_doRelease TRUE
_timestamp 2018-11-30 03:20:39
authored [InstanceEdit:179395] D'Eustachio, P, Gay, NJ, Gale M, Jr, Zwaginga, JJ, 2006-04-19 04:09:58
compartment [Compartment:984] extracellular region [Compartment:876] plasma membrane
created [InstanceEdit:168943] de Bono, B, 2005-11-22 18:44:27
edited [InstanceEdit:2603258] Shamovsky, V, 2012-11-19
input [Complex:168949] TLR6:TLR2 [plasma membrane] [Homo sapiens] [Complex:2559461] TLR6/2 ligand:CD14:CD36 [plasma membrane] [Homo sapiens]
literatureReference [LiteratureReference:180828] Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2 [LiteratureReference:181143] Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin [LiteratureReference:181127] Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components [LiteratureReference:181125] Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis [LiteratureReference:181032] Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2 [LiteratureReference:181943] Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6 [LiteratureReference:9630198] The proinflammatory cytokine response to Chlamydia trachomatis elementary bodies in human macrophages is partly mediated by a lipoprotein, the macrophage infectivity potentiator, through TLR2/TLR1/TLR6 and CD14
modified [InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:177514] Gopinathrao, G, 2006-03-31 14:29:10 [InstanceEdit:177804] Gillespie, ME, 2006-04-07 03:21:26 [InstanceEdit:181411] de Bono, B, 2006-06-09 11:18:43 [InstanceEdit:181939] D'Eustachio, P, 2006-07-03 21:35:13 [InstanceEdit:181965] de Bono, B, 2006-07-04 10:37:21 [InstanceEdit:182627] de Bono, B, 2006-07-11 10:20:29 [InstanceEdit:182631] de Bono, B, 2006-07-11 11:29:15 [InstanceEdit:188963] Gopinathrao, G, 2006-11-01 22:14:37 [InstanceEdit:1020101] Shamovsky, V, 2010-11-16 [InstanceEdit:1094899] Shamovsky, V, 2010-11-29 [InstanceEdit:1095197] Shamovsky, V, 2010-11-30 [InstanceEdit:2559485] Shamovsky, V, 2012-11-02 [InstanceEdit:2559493] Shamovsky, V, 2012-11-02 [InstanceEdit:2629678] Shamovsky, V, 2012-11-20 [InstanceEdit:5621483] Shamovsky, V, 2014-08-29 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9628835] Shamovsky, Veronica, 2018-11-13 [InstanceEdit:9630197] Shamovsky, Veronica, 2018-11-30 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name TLR6:TLR2 is recruited to ligand:CD14:CD36
output [Complex:181410] TLR6:TLR2:ligand:CD14:CD36 [plasma membrane] [Homo sapiens]
precedingEvent
relatedSpecies [Species:181384] Chlamydia trachomatis
releaseDate 2005-06-13
reviewed [InstanceEdit:181939] D'Eustachio, P, 2006-07-03 21:35:13 [InstanceEdit:1095192] Gillespie, ME, 2010-11-30
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:358735] R-HSA-168950.5
summation [Summation:181955] TLR2 - in combination with TLR6 - plays a major role in reco...
(hasEvent) [Pathway:168188] Toll Like Receptor TLR6:TLR2 Cascade [Homo sapiens]
(precedingEvent) [Reaction:2201316] Activated TLR2/4 interacts with MAL (TIRAP) [Homo sapiens]
(updatedInstance) [_UpdateTracker:9778018] Update Tracker - [Reaction:168950] TLR6:TLR2 is recruited to ligand:CD14:CD36 - v68:[addLiteratureReference] [_UpdateTracker:9788272] Update Tracker - [Reaction:168950] TLR6:TLR2 is recruited to ligand:CD14:CD36 - v43:[addLiteratureReference, add_removeInput, modifyText]
[Change default viewing format]
List...
Protein identifiers
ChEBI identifiers
KEGG COMPOUND identifiers
No pathways have been reviewed or authored by TLR6:TLR2 is recruited to ligand:CD14:CD36 (168950)