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Details on Person Viral dsRNA:TLR3:TRIF complex recruits RIP1

Class:IdReaction:168930
_displayNameViral dsRNA:TLR3:TRIF complex recruits RIP1
_doReleaseTRUE
_timestamp2017-12-01 23:37:01
authored[InstanceEdit:167907] Luo, F, 2005-11-10 11:23:18
compartment[Compartment:74700] endosome membrane
[Compartment:70101] cytosol
created[InstanceEdit:168919] de Bono, B, 2005-11-22 18:36:47
edited[InstanceEdit:450361] Shamovsky, V, 2009-12-16
input[EntityWithAccessionedSequence:168651] RIPK1 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:168651] RIPK1 [cytosol] [Homo sapiens]
[Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] [Homo sapiens]
literatureReference[LiteratureReference:165954] RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B
[LiteratureReference:433849] Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation
modified[InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11
[InstanceEdit:177514] Gopinathrao, G, 2006-03-31 14:29:10
[InstanceEdit:177635] Gillespie, ME, 2006-04-03 17:51:51
[InstanceEdit:177638] Gillespie, ME, 2006-04-03 17:52:42
[InstanceEdit:177650] Gillespie, ME, 2006-04-03 18:36:10
[InstanceEdit:177681] Gillespie, ME, 2006-04-03 21:05:17
[InstanceEdit:177884] Gillespie, ME, 2006-04-11 02:04:55
[InstanceEdit:188963] Gopinathrao, G, 2006-11-01 22:14:37
[InstanceEdit:450362] Shamovsky, V, 2009-12-16
[InstanceEdit:500577] Shamovsky, V, 2010-02-04
[InstanceEdit:525853] Shamovsky, V, 2010-02-22
[InstanceEdit:532463] Shamovsky, V, 2010-02-27
[InstanceEdit:1008271] Shamovsky, V, 2010-11-10
[InstanceEdit:2457719] Shamovsky, V, 2012-08-28
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8979781] Shamovsky, Veronica, 2017-02-27
[InstanceEdit:9014357] Shamovsky, Veronica, 2017-07-28
[InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01
[InstanceEdit:9031726] D'Eustachio, Peter, 2017-12-01
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameViral dsRNA:TLR3:TRIF complex recruits RIP1
output[Complex:177649] viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane] [Homo sapiens]
precedingEvent
regulatedBy[NegativeRegulation:450301] Negative regulation by 'RIPK3 [cytosol]'
regulationReference[RegulationReference:9642297] Negative regulation by 'RIPK3 [cytosol]' RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B
relatedSpecies[Species:5229092] Hepatitis B virus
[Species:5621375] Hepatitis C Virus
[Species:5689680] Human herpesvirus 1
[Species:5617433] Rotavirus
[Species:9031716] Influenza A virus
releaseDate2010-12-14
reviewed[InstanceEdit:188961] Gay, NJ, 2006-04-24 16:48:17
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:442879] Shamovsky, V, 2009-09-29
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8886018] R-HSA-168930.5
summation[Summation:433930] RIP1 is recruited to the activated TLR receptor by binding t...
(hasEvent)[Pathway:168927] TICAM1, RIP1-mediated IKK complex recruitment [Homo sapiens]
(precedingEvent)[Reaction:168910] RIP1 facilitates IKK complex phosphorylation [Homo sapiens]
[Reaction:9014342] K63-linked ubiquitination of RIP1 bound to the activated TLR complex [Homo sapiens]
(replacementInstances)[_Deleted:765400] Deletion of instance: 168911
(updatedInstance)[_UpdateTracker:9790111] Update Tracker - [Reaction:168930] Viral dsRNA:TLR3:TRIF complex recruits RIP1 - v35:[modifyText]
[_UpdateTracker:9790255] Update Tracker - [Reaction:168930] Viral dsRNA:TLR3:TRIF complex recruits RIP1 - v34:[modifyText]
[_UpdateTracker:9791016] Update Tracker - [Reaction:168930] Viral dsRNA:TLR3:TRIF complex recruits RIP1 - v32:[addLiteratureReference, addRegulator, add_removeSummation]
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