Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person viral dsRNA:TLR3:TICAM1 [endosome membrane]
Class:Id Complex:168907
_displayName viral dsRNA:TLR3:TICAM1 [endosome membrane]
_timestamp 2017-12-01 23:52:48
authored [InstanceEdit:167907] Luo, F, 2005-11-10 11:23:18
compartment [Compartment:74700] endosome membrane
created [InstanceEdit:168919] de Bono, B, 2005-11-22 18:36:47
hasComponent
literatureReference [LiteratureReference:2428862] Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta
modified [InstanceEdit:177521] Gillespie, ME, 2006-03-31 20:24:30 [InstanceEdit:450362] Shamovsky, V, 2009-12-16 [InstanceEdit:1564930] Shamovsky, V, 2011-09-06 [InstanceEdit:2428907] Shamovsky, V, 2012-08-08 [InstanceEdit:9013885] Shamovsky, Veronica, 2017-07-26 [InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9031727] D'Eustachio, Peter, 2017-12-01
name viral dsRNA:TLR3:TICAM1 viral dsRNA:TLR3:TRIF
relatedSpecies [Species:5229092] Hepatitis B virus [Species:5621375] Hepatitis C Virus [Species:5689680] Human herpesvirus 1 [Species:5617433] Rotavirus [Species:9031716] Influenza A virus
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:371234] R-HSA-168907.3
(hasComponent) [Complex:168918] TRIF:TRAM:activated TLR3 [plasma membrane] [Homo sapiens] [Complex:177649] viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane] [Homo sapiens] [Complex:177693] viral dsRNA:TLR3:TRIF:TRAF6 [endosome membrane] [Homo sapiens] [Complex:450309] viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] [Homo sapiens] [Complex:9013891] activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] [Homo sapiens] [Complex:9013893] activated TLR3:TRIF:RIP1:FADD [endosome membrane] [Homo sapiens] [Complex:9013960] viral dsRNA:TLR3:TICAM1:RIPK3 [endosome membrane] [Homo sapiens] [Complex:9013984] TRAF3:TICAM1:viral dsRNA:TLR3 [endosome membrane] [Homo sapiens] [Complex:9013989] K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] [Homo sapiens] [Complex:9014322] SARM:TICAM1:viral dsRNA:TLR3 [endosome membrane] [Homo sapiens]
(hasMember) [CandidateSet:9013962] TICAM1:activated TLR3 complexes [endosome membrane] [Homo sapiens]
(input) [Reaction:168930] Viral dsRNA:TLR3:TRIF complex recruits RIP1 [Homo sapiens] [Reaction:177694] Viral dsRNA:TLR3:TICAM1 complex recruits TRAF6 [Homo sapiens] [FailedReaction:5602624] Defective TRAF3 does not transmit the signal [Homo sapiens] [Reaction:9013992] TRAF3 binds to TRIF:activated TLR3 complex [Homo sapiens] [Reaction:9014320] SARM binds viral dsRNA:TLR3:TICAM1 [Homo sapiens]
(output) [Reaction:168929] Viral dsRNA:TLR3 recruits TRIF (TICAM1) [Homo sapiens] [Reaction:847070] Phosphorylated TAK1 dissociates from the TLR3 receptor complex [Homo sapiens]
(replacementInstances) [_Deleted:9910833] Deletion of instance: 2201340
(updatedInstance) [_UpdateTracker:9868789] Update Tracker - [Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] - v32:[add_removeCompartment, add_removeHasComponent, updateContainedComponent] [_UpdateTracker:9870824] Update Tracker - [Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] - v38:[modifyName, updateContainedComponent] [_UpdateTracker:9871004] Update Tracker - [Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] - v39:[updateContainedComponent] [_UpdateTracker:9872885] Update Tracker - [Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [_UpdateTracker:9892745] Update Tracker - [Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] - v54:[updateContainedComponent] [_UpdateTracker:9897324] Update Tracker - [Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] - v62:[addName, updateContainedComponent] [_UpdateTracker:9898089] Update Tracker - [Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] - v63:[updateContainedComponent] [_UpdateTracker:9898823] Update Tracker - [Complex:168907] viral dsRNA:TLR3:TICAM1 [endosome membrane] - v64:[updateContainedComponent]
[Change default viewing format]
List...
Protein identifiers
No pathways have been reviewed or authored by viral dsRNA:TLR3:TICAM1 [endosome membrane] (168907)