Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person RIPK1 [cytosol]

Class:IdEntityWithAccessionedSequence:168651
_displayNameRIPK1 [cytosol]
_timestamp2015-06-10 10:13:30
compartment[Compartment:70101] cytosol
created[InstanceEdit:168695] Gillespie, ME, 2005-11-17 05:54:29
endCoordinate671
modified[InstanceEdit:3006723] Jassal, B, 2013-02-01
[InstanceEdit:3132750] Wu, G, 2013-02-13
[InstanceEdit:5675036] Shamovsky, V, 2015-02-15
[InstanceEdit:6782982] Jupe, Steve, 2015-06-10
nameRIPK1
Receptor-interacting serine/threonine-protein kinase 1
receptor interacting protein 1 kinase
RIP1
referenceEntity[ReferenceGeneProduct:63119] UniProt:Q13546 RIPK1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:364408] R-HSA-168651.2
startCoordinate1
(activeUnit)[CatalystActivity:5218883] protein serine/threonine kinase activity of RIPK1:RIPK3 [cytosol]
(hasComponent)[Complex:140935] TRAF2:TRADD:RIPK1 [cytosol] [Homo sapiens]
[Complex:140946] TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] [Homo sapiens]
[Complex:168905] RIP1:TRIF:TRAM:Activated TLR3 [plasma membrane] [Homo sapiens]
[Complex:168912] RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] [Homo sapiens]
[Complex:918291] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:RIPK1:FADD [mitochondrial outer membrane] [Homo sapiens]
[Complex:918293] IPS-1:RIP-1/FADD [mitochondrial outer membrane] [Homo sapiens]
[Complex:933466] IPS-1:RIP-1/FADD:Casp-8/10 prodomain [mitochondrial outer membrane] [Homo sapiens]
[Complex:933475] IPS-1:RIP-1/FADD:procaspase-8/10 [mitochondrial outer membrane] [Homo sapiens]
[Complex:933477] IPS-1:RIP-1/FADD:procaspase-8/10 dimer [mitochondrial outer membrane] [Homo sapiens]
[Complex:1810470] dsDNA:ZBP1:RIP1:RIP3 [cytosol] [Homo sapiens]
List all 22 refering instances
(hasMember)[DefinedSet:5690188] RIPK1, DDX58 [cytosol] [Homo sapiens]
[DefinedSet:6782832] TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] [Homo sapiens]
(input)[Reaction:83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 [Homo sapiens]
[Reaction:168921] TRIF:activated TLR3/TLR4 complex recruits RIP1 [Homo sapiens]
[Reaction:168930] Viral dsRNA:TLR3:TRIF complex recruits RIP1 [Homo sapiens]
[Reaction:168934] MAVS interacts with RIPK1 and FADD [Homo sapiens]
[Reaction:1810457] ZBP1(DAI) recruits RIP1 and RIP3 [Homo sapiens]
[Reaction:5213462] RIPK3 binds RIPK1 [Homo sapiens]
[Reaction:5334740] HPV Suppressed TNF:TNF-R1 binds TRADD, TRAF2 and RIP [Homo sapiens]
[Reaction:5634221] TRAF1 binds TRAF2 within TNFR1 signaling complex [Homo sapiens]
[Reaction:5634230] TRAF1(164-416) binds TRAF2 within TNFR1 signaling complex [Homo sapiens]
[Reaction:9687465] HSV1 RIR1 binds RIPK1 [Homo sapiens]
List all 11 refering instances
(updatedInstance)[_UpdateTracker:9880048] Update Tracker - [EntityWithAccessionedSequence:168651] RIPK1 [cytosol] - v44:[addEndCoordinate, addStartCoordinate, modifyName]
[_UpdateTracker:9890013] Update Tracker - [EntityWithAccessionedSequence:168651] RIPK1 [cytosol] - v52:[modifyName]
[Change default viewing format]
No pathways have been reviewed or authored by RIPK1 [cytosol] (168651)
Follow Reactome