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Details on Person Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.

Class:Id	Reaction:168440
_displayName	Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.
_doRelease	TRUE
_timestamp	2010-02-27 19:28:57
authored	[InstanceEdit:168344] Luo, F, 2005-11-16 12:05:41
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:168513] Gillespie, ME, 2005-11-17 05:52:23
edited	[InstanceEdit:450361] Shamovsky, V, 2009-12-16
input	[EntityWithAccessionedSequence:450243] p-T69,T71-ATF2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:450237] p-S63,S73-JUN [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:169947] Regulatory mechanisms involved in activator-protein-1 (AP-1)-mediated activation of glutathione-S-transferase gene expression by chemical agents
modified	[InstanceEdit:168813] Gillespie, ME, 2005-11-17 20:21:18 [InstanceEdit:168819] Gillespie, ME, 2005-11-17 20:24:16 [InstanceEdit:168844] Wu, G, 2005-11-17 21:15:51 [InstanceEdit:170020] Gillespie, ME, 2005-12-19 05:16:24 [InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11 [InstanceEdit:177475] Gopinathrao, G, 2006-03-30 20:13:46 [InstanceEdit:177514] Gopinathrao, G, 2006-03-31 14:29:10 [InstanceEdit:177708] Gillespie, ME, 2006-04-04 05:55:29 [InstanceEdit:188963] Gopinathrao, G, 2006-11-01 22:14:37 [InstanceEdit:450361] Shamovsky, V, 2009-12-16 [InstanceEdit:500514] Shamovsky, V, 2010-02-04 [InstanceEdit:525843] Shamovsky, V, 2010-02-22 [InstanceEdit:532463] Shamovsky, V, 2010-02-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.
output	[Complex:450262] p-2S-cJUN:p-2T-ATF2 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:168136] Activated JNKs phosphorylate c-JUN [Homo sapiens] [Reaction:450348] Activated human JNKs migrate to nucleoplasm [Homo sapiens] [Reaction:168053] Phosphorylated MAPKs phosphorylate ATF-2 [Homo sapiens] [Reaction:450348] Activated human JNKs migrate to nucleoplasm [Homo sapiens] [Reaction:450333] Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 [Homo sapiens] [BlackBoxEvent:5674387] Phosphorylated MAPKs translocate into the nucleus [Homo sapiens]
releaseDate	2010-03-16
reviewed	[InstanceEdit:188961] Gay, NJ, 2006-04-24 16:48:17
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:450323] Shamovsky, V, 2009-12-16
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360282] R-HSA-168440.2
summation	[Summation:178671] At the beginning of this reaction, 1 molecule of 'c-Jun-P', ...
(hasEvent)	[Pathway:450341] Activation of the AP-1 family of transcription factors [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9791053] Update Tracker - [Reaction:168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - v32:[add_removeInput, add_removeOutput]
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