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Details on Person Docking and transport of the RNP:Karyopherin complex through the nuclear pore

Class:Id	Reaction:168337
_displayName	Docking and transport of the RNP:Karyopherin complex through the nuclear pore
_doRelease	TRUE
_timestamp	2017-12-01 23:34:16
authored	[InstanceEdit:168269] Gillespie, ME, 2005-11-14 17:18:07
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:168327] 2007-04-16 22:35:07
disease	[Disease:1660558] influenza
goBiologicalProcess	[GO_BiologicalProcess:2454643] intracellular transport of virus
input	[Complex:188853] RNP:Karyopherin alpha:Karyopherin beta complex [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:169533] Two signals mediate nuclear localization of influenza virus (A/WSN/33) polymerase basic protein 2
modified	[InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22 [InstanceEdit:169592] Gillespie, ME, 2005-11-30 03:44:54 [InstanceEdit:169852] 2007-04-16 22:35:07 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170318] D'Eustachio, P, 2006-01-05 18:45:23 [InstanceEdit:188888] Gillespie, ME, 2006-10-28 01:26:32 [InstanceEdit:188900] Gillespie, ME, 2006-10-29 16:08:10 [InstanceEdit:188902] Gillespie, ME, 2006-10-29 16:39:41 [InstanceEdit:188906] Gillespie, ME, 2006-10-29 16:43:14 [InstanceEdit:188941] Gopinathrao, G, 2006-10-30 22:24:14 [InstanceEdit:193028] Gillespie, ME, 2007-02-12 18:15:57 [InstanceEdit:3632908] Gillespie, ME, 2013-05-28 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:8942680] Gillespie, Marc E, 2016-10-19 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9031726] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Docking and transport of the RNP:Karyopherin complex through the nuclear pore
output	[Complex:188844] RNP:Karyopherin alpha:Karyopherin beta complex [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:168317] Recruitment of Karyopherin Beta to form a Trimeric Complex [Homo sapiens] [Reaction:168297] Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein [Homo sapiens]
regulatedBy	[Requirement:188869] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2006-01-23
reviewed	[InstanceEdit:188904] Squires, B, 2006-10-29 16:42:09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361836] R-HSA-168337.5
summation	[Summation:179341] These RNPs (10-20nm wide) are too large to passively diffuse...
(hasEvent)	[Pathway:168271] Transport of Ribonucleoproteins into the Host Nucleus [Homo sapiens]
(precedingEvent)	[Reaction:168310] Release of the RNP into the host cell nucleus [Homo sapiens]
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No pathways have been reviewed or authored by Docking and transport of the RNP:Karyopherin complex through the nuclear pore (168337)