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Details on Person Assembly of an Active Transcription Complex
Class:Id Reaction:168326
_displayName Assembly of an Active Transcription Complex
_doRelease TRUE
_timestamp 2017-12-01 23:32:29
authored [InstanceEdit:193029] Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:168327] 2007-04-16 22:35:07
disease [Disease:1660558] influenza
goBiologicalProcess [GO_BiologicalProcess:6686] viral transcription
input [OtherEntity:158444] Mature intronless transcript derived mRNA [nucleoplasm] [Complex:192720] Viral Polymerase [nucleoplasm] [Influenza A virus] [Complex:193302] vRNA (Genomic):NP Complex [nucleoplasm] [Influenza A virus]
literatureReference [LiteratureReference:168991] Differential activation of the influenza virus polymerase via template RNA binding [LiteratureReference:169042] A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription [LiteratureReference:192737] RNA-dependent activation of primer RNA production by influenza virus polymerase: different regions of the same protein subunit constitute the two required RNA-binding sites [LiteratureReference:192890] The RNA polymerase of influenza a virus is stabilized by interaction with its viral RNA promoter [LiteratureReference:192648] Two separate sequences of PB2 subunit constitute the RNA cap-binding site of influenza virus RNA polymerase
modified [InstanceEdit:169043] D'Eustachio, P, 2005-11-22 21:20:38 [InstanceEdit:169475] Gillespie, ME, 2005-11-29 19:25:51 [InstanceEdit:169592] Gillespie, ME, 2005-11-30 03:44:54 [InstanceEdit:169852] 2007-04-16 22:35:07 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170325] D'Eustachio, P, 2006-01-05 18:46:03 [InstanceEdit:192929] 2007-04-09 15:04:30 [InstanceEdit:193028] Gillespie, ME, 2007-02-12 18:15:57 [InstanceEdit:193033] Gillespie, ME, 2007-02-12 19:40:55 [InstanceEdit:193305] Gillespie, ME, 2007-02-13 22:20:16 [InstanceEdit:450906] Gillespie, ME, 2009-12-22 [InstanceEdit:3632908] Gillespie, ME, 2013-05-28 [InstanceEdit:5601871] Gillespie, Marc E, 2014-06-13 [InstanceEdit:5617436] Gillespie, Marc E, 2014-08-08 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9031726] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Assembly of an Active Transcription Complex
output [Complex:192703] vRNA Transcription Complex [nucleoplasm] [Influenza A virus]
precedingEvent
regulatedBy [PositiveRegulation:192796] Positive regulation by 'RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm]' [PositiveRegulation:192819] Positive regulation by 'NP [nucleoplasm]'
relatedSpecies [Species:9031716] Influenza A virus
releaseDate 2006-01-23
reviewed [InstanceEdit:193030] Squires, B, 2007-02-12 19:39:22
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:360226] R-HSA-168326.5
summation [Summation:169032] The 5' end of the vRNA associates with a binding site on the...
(hasEvent) [Pathway:168325] Viral Messenger RNA Synthesis [Homo sapiens]
(precedingEvent) [Reaction:168280] Priming and Initiation of Transcription [Homo sapiens]
(updatedInstance) [_UpdateTracker:9792461] Update Tracker - [Reaction:168326] Assembly of an Active Transcription Complex - v21:[modifyText] [_UpdateTracker:9792521] Update Tracker - [Reaction:168326] Assembly of an Active Transcription Complex - v20:[addInput, addOutput, addRegulator, add_removeLiteratureReference, modifyText]
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