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Details on Person Conformation change in hemagglutinin freeing the fusion peptide of HA2

Class:Id	Reaction:168324
_displayName	Conformation change in hemagglutinin freeing the fusion peptide of HA2
_doRelease	TRUE
_timestamp	2017-12-01 23:34:11
compartment	[Compartment:171907] endosome lumen
created	[InstanceEdit:168327] 2007-04-16 22:35:07
disease	[Disease:1660558] influenza
input	[Complex:189171] Influenza A Viral Particle [endosome lumen] [Influenza A virus]
literatureReference	[LiteratureReference:189373] Membrane fusion mechanisms: the influenza hemagglutinin paradigm and its implications for intracellular fusion
modified	[InstanceEdit:169475] Gillespie, ME, 2005-11-29 19:25:51 [InstanceEdit:169852] 2007-04-16 22:35:07 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170318] D'Eustachio, P, 2006-01-05 18:45:23 [InstanceEdit:189185] Gillespie, ME, 2006-11-03 22:01:32 [InstanceEdit:189377] Gillespie, ME, 2006-11-07 20:20:06 [InstanceEdit:448549] Gillespie, ME, 2009-11-24 [InstanceEdit:3632908] Gillespie, ME, 2013-05-28 [InstanceEdit:5601871] Gillespie, Marc E, 2014-06-13 [InstanceEdit:5617436] Gillespie, Marc E, 2014-08-08 [InstanceEdit:8942680] Gillespie, Marc E, 2016-10-19 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9031726] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Conformation change in hemagglutinin freeing the fusion peptide of HA2
output	[Complex:189182] Influenza A Viral Particle With A Fusion Competent HA2 [endosome lumen] [Influenza A virus]
precedingEvent	[Reaction:168285] Clathrin-Mediated Pit Formation And Endocytosis Of The Influenza Virion [Homo sapiens] [Reaction:168272] Binding of the influenza virion to the host cell [Homo sapiens]
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2006-01-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358638] R-HSA-168324.4
summation	[Summation:179371] The low pH of the endosome causes the viral HA (hemagglutini...
(hasEvent)	[Pathway:168288] Fusion of the Influenza Virion to the Host Cell Endosome [Homo sapiens]
(precedingEvent)	[Reaction:168312] Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9792519] Update Tracker - [Reaction:168324] Conformation change in hemagglutinin freeing the fusion peptide of HA2 - v20:[addLiteratureReference, modifyText]
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