Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person Priming and Initiation of Transcription
Class:Id Reaction:168280
_displayName Priming and Initiation of Transcription
_doRelease TRUE
_timestamp 2017-12-01 23:35:17
authored [InstanceEdit:193029] Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05
catalystActivity [CatalystActivity:192665] RNA-directed RNA polymerase activity of Viral Polymerase [nucleoplasm]
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:168327] 2007-04-16 22:35:07
disease [Disease:1660558] influenza
goBiologicalProcess [GO_BiologicalProcess:6686] viral transcription
input [Complex:192703] vRNA Transcription Complex [nucleoplasm] [Influenza A virus]
literatureReference [LiteratureReference:169042] A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription [LiteratureReference:192761] Priming of influenza viral RNA transcription by capped heterologous RNAs [LiteratureReference:169020] Recombinant influenza virus polymerase: requirement of both 5' and 3' viral ends for endonuclease activity [LiteratureReference:192844] The active sites of the influenza cap-dependent endonuclease are on different polymerase subunits
modified [InstanceEdit:169043] D'Eustachio, P, 2005-11-22 21:20:38 [InstanceEdit:169475] Gillespie, ME, 2005-11-29 19:25:51 [InstanceEdit:169592] Gillespie, ME, 2005-11-30 03:44:54 [InstanceEdit:169852] 2007-04-16 22:35:07 [InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30 [InstanceEdit:170325] D'Eustachio, P, 2006-01-05 18:46:03 [InstanceEdit:192929] 2007-04-09 15:04:30 [InstanceEdit:193028] Gillespie, ME, 2007-02-12 18:15:57 [InstanceEdit:193033] Gillespie, ME, 2007-02-12 19:40:55 [InstanceEdit:193041] Gillespie, ME, 2007-02-12 21:04:16 [InstanceEdit:193305] Gillespie, ME, 2007-02-13 22:20:16 [InstanceEdit:3632908] Gillespie, ME, 2013-05-28 [InstanceEdit:5601870] Gillespie, Marc E, 2014-06-13 [InstanceEdit:5621512] Matthews, Lisa, 2014-08-29 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9031726] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Priming and Initiation of Transcription
output [Complex:192756] Initiated vRNA Transcription Complex [nucleoplasm] [Influenza A virus] [OtherEntity:193039] Mature intronless transcript derived mRNA with m7G cap removed [nucleoplasm]
precedingEvent
relatedSpecies [Species:9031716] Influenza A virus
releaseDate 2005-06-13
reviewed [InstanceEdit:193030] Squires, B, 2007-02-12 19:39:22
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:359467] R-HSA-168280.4
summation [Summation:168985] The host cell mRNA bound to viral RNA polymerase PB2 subunit...
(hasEvent) [Pathway:168325] Viral Messenger RNA Synthesis [Homo sapiens]
(precedingEvent) [BlackBoxEvent:168301] Elongation, Polyadenylation and Termination [Homo sapiens]
(updatedInstance) [_UpdateTracker:9792473] Update Tracker - [Reaction:168280] Priming and Initiation of Transcription - v20:[addCatalystActivity, addInput, addOutput, add_removeLiteratureReference, modifyText]
[Change default viewing format]
List...
Protein identifiers
ChEBI identifiers
KEGG COMPOUND identifiers
No pathways have been reviewed or authored by Priming and Initiation of Transcription (168280)