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Details on Person Phosphorylated MAPKs phosphorylate ATF-2

Class:IdReaction:168053
_displayNamePhosphorylated MAPKs phosphorylate ATF-2
_doReleaseTRUE
_timestamp2021-08-03 16:31:47
authored[InstanceEdit:167907] Luo, F, 2005-11-10 11:23:18
catalystActivity[CatalystActivity:167971] protein serine/threonine kinase activity of Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:168000] Gillespie, ME, 2005-11-10 16:24:09
edited[InstanceEdit:450361] Shamovsky, V, 2009-12-16
input[EntityWithAccessionedSequence:450336] ATF2 [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
literatureReference[LiteratureReference:170002] p38 MAPK signalling cascades: ancient roles and new functions
modified[InstanceEdit:170020] Gillespie, ME, 2005-12-19 05:16:24
[InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11
[InstanceEdit:177475] Gopinathrao, G, 2006-03-30 20:13:46
[InstanceEdit:177514] Gopinathrao, G, 2006-03-31 14:29:10
[InstanceEdit:177706] Gillespie, ME, 2006-04-04 05:54:52
[InstanceEdit:177804] Gillespie, ME, 2006-04-07 03:21:26
[InstanceEdit:188963] Gopinathrao, G, 2006-11-01 22:14:37
[InstanceEdit:450361] Shamovsky, V, 2009-12-16
[InstanceEdit:500556] Shamovsky, V, 2010-02-04
[InstanceEdit:525846] Shamovsky, V, 2010-02-22
[InstanceEdit:532463] Shamovsky, V, 2010-02-27
[InstanceEdit:9749431] Matthews, Lisa, 2021-08-03
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePhosphorylated MAPKs phosphorylate ATF-2
output[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
[EntityWithAccessionedSequence:450243] p-T69,T71-ATF2 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2010-03-16
reviewed[InstanceEdit:188961] Gay, NJ, 2006-04-24 16:48:17
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:450323] Shamovsky, V, 2009-12-16
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361840] R-HSA-168053.3
summation[Summation:179041] At the beginning of this reaction, 1 molecule of 'ATP', and ...
[Summation:450338] the Raf–MEK–ERK pathway induces phosphorylation of ATF2 Thr7...
(hasEvent)[Pathway:450341] Activation of the AP-1 family of transcription factors [Homo sapiens]
(precedingEvent)[BlackBoxEvent:168193] Transcriptional action of c-Jun-P and ATF-2-P induce IFNB [Homo sapiens]
[BlackBoxEvent:168197] Transcriptional action of c-Jun-P and ATF-1-P induce IFNA [Homo sapiens]
[Reaction:168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. [Homo sapiens]
[Reaction:8944397] p-T69,T71-ATF2 binds PTEN gene promoter [Homo sapiens]
(updatedInstance)[_UpdateTracker:9782233] Update Tracker - [Reaction:168053] Phosphorylated MAPKs phosphorylate ATF-2 - v59:[modifyText]
[_UpdateTracker:9789540] Update Tracker - [Reaction:168053] Phosphorylated MAPKs phosphorylate ATF-2 - v37:[modifyText]
[_UpdateTracker:9790865] Update Tracker - [Reaction:168053] Phosphorylated MAPKs phosphorylate ATF-2 - v32:[addSummation, add_removeInput, add_removeOutput]
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