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Details on Person C-ter TLR9 dimer:unmethylated CpG DNA [endosome membrane]

Class:Id	Complex:1679087
_displayName	C-ter TLR9 dimer:unmethylated CpG DNA [endosome membrane]
_timestamp	2012-08-13 01:39:28
compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:1679091] Shamovsky, V, 2011-10-19
hasComponent	[OtherEntity:167913] Unmethylated CpG DNA [endosome membrane] [Complex:1679581] C-ter-TLR9 dimer [endosome membrane] [Homo sapiens] [EntityWithAccessionedSequence:1679580] TLR9(?-1032) [endosome membrane] [Homo sapiens] [EntityWithAccessionedSequence:1679580] TLR9(?-1032) [endosome membrane] [Homo sapiens]
literatureReference	[LiteratureReference:1679106] Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains [LiteratureReference:2445194] Single molecule in vivo analysis of toll-like receptor 9 and CpG DNA interaction [LiteratureReference:1679137] TLR9 signals after translocating from the ER to CpG DNA in the lysosome [LiteratureReference:1679563] TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA [LiteratureReference:1679551] Negative regulation of signaling by a soluble form of toll-like receptor 9
modified	[InstanceEdit:1679583] Shamovsky, V, 2011-10-20 [InstanceEdit:2445241] Shamovsky, V, 2012-08-13
name	C-ter TLR9 dimer:unmethylated CpG DNA
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2017134] R-HSA-1679087.1
(hasMember)	[DefinedSet:975158] Activated TLR7-9 homodimers [endosome membrane] [Homo sapiens]
(input)	[Reaction:188002] Rab5-mediated recruitment of class III PI3K to TLR9 [Homo sapiens]
(output)	[Reaction:187895] Engulfed CpG DNA binds to endosomal C-ter TLR9 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9873324] Update Tracker - [Complex:1679087] C-ter TLR9 dimer:unmethylated CpG DNA [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent]
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No pathways have been reviewed or authored by C-ter TLR9 dimer:unmethylated CpG DNA [endosome membrane] (1679087)