Query author contributions in Reactome
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Details on Person Tat associates with the Cyclin T1 subunit of the cellular ki...
| Class:Id | Summation:167808 |
|---|---|
| _displayName | Tat associates with the Cyclin T1 subunit of the cellular ki... |
| _timestamp | 2006-01-15 13:14:00 |
| created | [InstanceEdit:167809] Matthews, L, 2005-11-09 01:31:41 |
| literatureReference | [LiteratureReference:167873] A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA |
| modified | [InstanceEdit:167880] Matthews, L, 2005-11-09 23:26:13 [InstanceEdit:167893] Matthews, L, 2005-11-10 09:15:05 [InstanceEdit:170768] Matthews, L, 2006-01-15 13:04:15 |
| text | Tat associates with the Cyclin T1 subunit of the cellular kinase complex TAK/P-TEFb and recruits this complex to the TAR sequence in the HIV-1 RNA (Wei et al. 1998). This association between TAT, TAR and TAK/P-TEFb is believed to bring the catalytic subunit of TAK/P-TEFb in close proximity to Pol II where it hyperphosphorylates the CTD of Pol II . |
| (summation) | [Reaction:167235] Formation of the P-TEFb(Cyclin T1:Cdk9) complex [Homo sapiens] |
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No pathways have been reviewed or authored by Tat associates with the Cyclin T1 subunit of the cellular ki... (167808)
