Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person HCK [cytosol]

Class:IdEntityWithAccessionedSequence:167708
_displayNameHCK [cytosol]
_timestamp2013-07-30 15:52:23
compartment[Compartment:70101] cytosol
created[InstanceEdit:167707] Gillespie, ME, 2005-11-01 21:41:07
endCoordinate526
modified[InstanceEdit:912661] Jupe, S, 2010-07-12
[InstanceEdit:3132750] Wu, G, 2013-02-13
[InstanceEdit:3632907] Wu, G, 2013-05-28
[InstanceEdit:4084660] Orlic-Milacic, M, 2013-07-30
nameHCK
Hck-1
referenceEntity[ReferenceGeneProduct:56394] UniProt:P08631 HCK [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:362413] R-HSA-167708.1
startCoordinate2
(hasCandidate)[CandidateSet:912625] FYN-like kinases [cytosol] [Homo sapiens]
(hasComponent)[Complex:200872] Hck-1:Nef [cytosol] [Homo sapiens]
[Complex:9609280] Active FLT3:HCK [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:912670] FYN, HCK, LYN [cytosol] [Homo sapiens]
[DefinedSet:1861597] Src family kinases (SFKs) [cytosol] [Homo sapiens]
[DefinedSet:9817990] FYN,HCK,SRC,YES1 [cytosol] [Homo sapiens]
(input)[Reaction:200858] Nef Binds and activates the Src-family tyrosine kinase Hck [Homo sapiens]
[BlackBoxEvent:9609274] Active FLT3 binds HCK [Homo sapiens]
[BlackBoxEvent:9676071] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK [Homo sapiens]
(updatedInstance)[_UpdateTracker:9869776] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v34:[addName]
[_UpdateTracker:9877567] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v44:[addEndCoordinate, addStartCoordinate]
[_UpdateTracker:9885249] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v45:[addName]
[_UpdateTracker:9887827] Update Tracker - [EntityWithAccessionedSequence:167708] HCK [cytosol] - v46:[removeName]
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No pathways have been reviewed or authored by HCK [cytosol] (167708)