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Details on Person PLCG1 [plasma membrane]
Class:Id EntityWithAccessionedSequence:167682
_displayName PLCG1 [plasma membrane]
_timestamp 2013-08-01 13:07:54
compartment [Compartment:876] plasma membrane
created [InstanceEdit:167673] Jassal, Bijay, 2005-11-01
endCoordinate 1290
modified [InstanceEdit:1483057] Orlic-Milacic, Marija, 2011-08-12 [InstanceEdit:1604562] Williams, MG, 2011-09-19 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:4084891] Orlic-Milacic, M, 2013-08-01
name PLCG1 Phospholipase C gamma 1 PLC1
referenceEntity [ReferenceGeneProduct:61708] UniProt:P19174 PLCG1 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:367798] R-HSA-167682.1
startCoordinate 2
(activeUnit) [CatalystActivity:186772] phosphatidylinositol-4,5-bisphosphate phospholipase C activity of PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane]
(hasComponent) [Complex:167687] Active TrkA receptor:PLCG1 complex [plasma membrane] [Homo sapiens] [Complex:186795] PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] [Homo sapiens] [Complex:190895] Activated FGFR:PLCG1 [plasma membrane] [Homo sapiens] [Complex:1247845] Ligand-responsive p-6Y-EGFR mutants:PLCG1 [plasma membrane] [Homo sapiens] [Complex:1839061] Activated FGFR1 mutants and fusions:PLCG1 [cytosol] [Homo sapiens] [Complex:2023858] PLCG1:Ca2+ [plasma membrane] [Homo sapiens] [Complex:2077381] Activated FGFR mutants:PLCG1 [plasma membrane] [Homo sapiens] [Complex:5637698] p-5Y-EGFRvIII:PLCG1 [plasma membrane] [Homo sapiens] [Complex:5654155] activated FGFR1:PLCG1 [plasma membrane] [Homo sapiens] [Complex:5654162] activated FGFR2:PLCG1 [plasma membrane] [Homo sapiens]
(input) [Reaction:167674] Binding of PLCG1 to active TrkA receptor [Homo sapiens] [Reaction:186765] PLC-gamma binds to the active receptor [Homo sapiens] [BlackBoxEvent:593690] Phosphorylation of PLCgamma by Netrin-1 [Homo sapiens] [Reaction:1247841] PLCG1 binds to ligand-responsive p-6Y-EGFR mutants [Homo sapiens] [Reaction:1839094] Activated FGFR1 mutants and fusions bind PLCG1 [Homo sapiens] [Reaction:5637792] PLC-gamma 1 binds to p-EGFRvIII mutant [Homo sapiens] [Reaction:5654159] Activated FGFR2 binds PLCG1 [Homo sapiens] [Reaction:5654163] Activated FGFR4 binds PLCG1 [Homo sapiens] [Reaction:5654167] Activated FGFR1 binds PLCG1 [Homo sapiens] [Reaction:5654224] Activated FGFR3 binds PLCG1 [Homo sapiens]
(updatedInstance) [_UpdateTracker:9870198] Update Tracker - [EntityWithAccessionedSequence:167682] PLCG1 [plasma membrane] - v38:[addName] [_UpdateTracker:9871146] Update Tracker - [EntityWithAccessionedSequence:167682] PLCG1 [plasma membrane] - v39:[addName, modifyEndCoordinate, modifyStartCoordinate] [_UpdateTracker:9881199] Update Tracker - [EntityWithAccessionedSequence:167682] PLCG1 [plasma membrane] - v45:[addName] [_UpdateTracker:9887970] Update Tracker - [EntityWithAccessionedSequence:167682] PLCG1 [plasma membrane] - v46:[removeName]
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No pathways have been reviewed or authored by PLCG1 [plasma membrane] (167682)