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Details on Person PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane

Class:IdReaction:1676206
_displayNamePI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane
_doReleaseTRUE
_timestamp2012-05-31 09:54:03
authored[InstanceEdit:1678579] Williams, MG, 2011-10-18
catalystActivity[CatalystActivity:1806261] 1-phosphatidylinositol-4-phosphate 3-kinase activity of PIK3C2A:Ca2+/Mg2+ [cytosol]
compartment[Compartment:171062] early endosome membrane
[Compartment:70101] cytosol
created[InstanceEdit:1676083] Williams, MG, 2011-10-17
edited[InstanceEdit:1482514] Williams, MG, 2011-08-12
input[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:1806180] PI4P [early endosome membrane]
isChimericFALSE
literatureReference[LiteratureReference:1676205] PI3KC2?, a class II PI3K, is required for dynamin-independent internalization pathways
[LiteratureReference:1675904] Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors
modified[InstanceEdit:1678578] Williams, MG, 2011-10-18
[InstanceEdit:1806251] Williams, MG, 2011-10-24
[InstanceEdit:1967225] Williams, MG, 2011-11-04
[InstanceEdit:2247961] D'Eustachio, P, 2012-05-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane
output[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:1806238] PI(3,4)P2 [early endosome membrane]
precedingEvent
releaseDate2012-06-12
reviewed[InstanceEdit:2247963] Wakelam, Michael, 2012-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2295303] R-HSA-1676206.2
summation[Summation:1675958] At the early endosome membrane, phosphatidylinositol-4-phosp...
(hasEvent)[Pathway:1660516] Synthesis of PIPs at the early endosome membrane [Homo sapiens]
(precedingEvent)[Reaction:1676162] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane [Homo sapiens]
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