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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person LCK [cytosol]

Class:IdEntityWithAccessionedSequence:167609
_displayNameLCK [cytosol]
_timestamp2013-01-30 16:43:23
compartment[Compartment:70101] cytosol
created[InstanceEdit:167538] Gillespie, ME, 2005-10-20 18:11:21
endCoordinate509
modified[InstanceEdit:167706] Gillespie, ME, 2005-11-01 21:01:20
[InstanceEdit:3006553] Jupe, S, 2013-01-30
nameLCK
Lymphocyte specific tyrosine kinase
referenceEntity[ReferenceGeneProduct:58457] UniProt:P06239 LCK [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:366906] R-HSA-167609.1
startCoordinate1
(activeUnit)[CatalystActivity:202226] protein tyrosine kinase activity of Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane]
(hasCandidate)[CandidateSet:453105] SHC kinases in IL2 signaling [cytosol] [Homo sapiens]
(hasComponent)[Complex:167529] CD4:Lck Complex [plasma membrane] [Homo sapiens]
[Complex:200922] Lck:Nef [cytosol] [Homo sapiens]
[Complex:202157] Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] [Homo sapiens]
[Complex:539005] IL2RB:LCK [plasma membrane] [Homo sapiens]
[Complex:8982907] IL7R:FYN:LCK [plasma membrane] [Homo sapiens]
[Complex:9706263] active FLT3:LCK [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:211064] Src family tyrosine kinases (SFKs) [cytosol] [Homo sapiens]
[DefinedSet:389743] LCK, CSK [cytosol] [Homo sapiens]
[DefinedSet:434838] p-Y348-SYK/LCK [cytosol] [Homo sapiens]
[DefinedSet:2395419] FYN,LCK [cytosol] [Homo sapiens]
[DefinedSet:2396556] SYK/LCK/ZAP-70 [cytosol] [Homo sapiens]
[CandidateSet:5607667] Src family tyrosine kinases (SFKs) [cytosol] [Homo sapiens]
[CandidateSet:9018917] RHOH effectors [cytosol] [Homo sapiens]
(input)[Reaction:200954] Nef Binds and activates the Src-family tyrosine kinase Lck [Homo sapiens]
[Reaction:204912] Interaction of pAxl and Lck [Homo sapiens]
[Reaction:539047] DO NOT RELEASE - IL2R beta binds LCK [Homo sapiens]
[BlackBoxEvent:8983012] FYN and LCK bind IL7R [Homo sapiens]
[Reaction:9706312] Active FLT3 binds to LCK [Homo sapiens]
(output)[Reaction:167566] Nef mediated disruption of CD4:Lck Complex [Homo sapiens]
(physicalEntity)[CatalystActivity:422516] protein tyrosine kinase activity of LCK [cytosol]
[CatalystActivity:507933] non-membrane spanning protein tyrosine kinase activity of LCK [cytosol]
(updatedInstance)[_UpdateTracker:9879650] Update Tracker - [EntityWithAccessionedSequence:167609] LCK [cytosol] - v44:[addEndCoordinate, addStartCoordinate, modifyName]
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No pathways have been reviewed or authored by LCK [cytosol] (167609)