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Details on Person Degradation of CD4

Class:IdBlackBoxEvent:167601
_displayNameDegradation of CD4
_doReleaseTRUE
_timestamp2014-12-12 21:44:01
authored[InstanceEdit:200905] Gillespie, ME, 2007-07-25 19:42:36
compartment[Compartment:70101] cytosol
created[InstanceEdit:167538] Gillespie, ME, 2005-10-20 18:11:21
disease[Disease:1660559] Human immunodeficiency virus infectious disease
input[Complex:167554] Internalized CD4:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane] [Homo sapiens]
literatureReference[LiteratureReference:182238] Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
modified[InstanceEdit:167721] Gillespie, ME, 2005-11-01 21:42:00
[InstanceEdit:169296] Vastrik, I, 2005-11-28 11:33:22
[InstanceEdit:170174] Gopinathrao, G, 2005-12-25 02:17:30
[InstanceEdit:170617] Gopinathrao, G, 2006-01-08 02:23:40
[InstanceEdit:177473] Gopinathrao, G, 2006-03-30 18:00:11
[InstanceEdit:182300] Gillespie, ME, 2006-07-06 21:32:56
[InstanceEdit:182793] Gillespie, ME, 2006-07-18 19:30:59
[InstanceEdit:194433] Schmidt, EE, 2007-03-13 12:36:50
[InstanceEdit:200904] Gillespie, ME, 2007-07-25 19:41:48
[InstanceEdit:200905] Gillespie, ME, 2007-07-25 19:42:36
[InstanceEdit:200907] Gillespie, ME, 2007-07-25 21:01:05
[InstanceEdit:201389] Gillespie, ME, 2007-08-07 14:42:02
[InstanceEdit:201413] Gopinathrao, G, 2007-08-08 14:30:28
[InstanceEdit:947461] Gillespie, ME, 2010-09-06
[InstanceEdit:3076315] Gillespie, ME, 2013-02-06
[InstanceEdit:5621512] Matthews, Lisa, 2014-08-29
[InstanceEdit:5656435] Gillespie, Marc E, 2014-12-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDegradation of CD4
output[EntityWithAccessionedSequence:167605] myristoylated nef [cytosol] [Human immunodeficiency virus 1]
[EntityWithAccessionedSequence:167578] ATP6V1H [cytosol] [Homo sapiens]
[Complex:167712] AP-2 Complex [cytosol] [Homo sapiens]
precedingEvent
relatedSpecies[Species:164493] Human immunodeficiency virus 1
releaseDate2007-08-21
reviewed[InstanceEdit:201388] Skowronski, J, 2007-08-07 14:33:41
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359163] R-HSA-167601.2
summation[Summation:201383] CD4 is degraded
(hasEvent)[Pathway:167590] Nef Mediated CD4 Down-regulation [Homo sapiens]
(updatedInstance)[_UpdateTracker:9787929] Update Tracker - [BlackBoxEvent:167601] Degradation of CD4 - v44:[add_removeOutput]
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